We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
case report of refractory angina in a patient with diabetes and apical hypertrophic cardiomyopathy.
- Authors
Jex, Nicholas; Chowdhary, Amrit; Thirunavukarasu, Sharmaine; Levelt, Eylem
- Abstract
Background Using serial imaging over time, this case reviews the natural history of co-morbid Type two diabetes (T2D) and apical hypertrophic cardiomyopathy (HCM) and assesses the potential combined impact on myocardial structure and perfusion. Case summary A 59-year-old patient with concomitant T2D and an apical phenotype of HCM was seen over a 11-year period with a significant burden of anginal chest pain. Chest pain was refractory to anti-anginal medical therapy and persisted at on-going follow-up. Multi-modality imaging demonstrated significant deterioration in coronary microvascular function and increased myocardial scar burden despite unobstructed epicardial coronary arteries. Discussion Comorbidity with T2D and apical HCM resulted in a significant increase in myocardial fibrosis and deterioration in coronary microvascular function.
- Subjects
HYPERTROPHIC cardiomyopathy; PEOPLE with diabetes; TAKOTSUBO cardiomyopathy; ANGINA pectoris; CHEST pain; CARDIAC magnetic resonance imaging; CORONARY arteries
- Publication
European Heart Journal Case Reports, 2022, Vol 6, Issue 8, p1
- ISSN
2514-2119
- Publication type
Article
- DOI
10.1093/ehjcr/ytac347