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- Title
Potential problems and pitfalls with the use of S-nitrosoglutathione and other S-nitrosothiols in physiology-oriented basic science.
- Authors
Tsikas, Dimitrios
- Abstract
The article discusses research being done on the use of S-nitrosoglutathione (GSNO) and other S-nitrosothiols in the field of physiology. It references the study "Modulation of Contractile Apparatus Ca2+ Sensitivity and Disruption of Excitation-Contraction Coupling by S-nitrosoglutathione in Rat Muscle Fibres," by T. L. Dutka, J. P. Mollica, G. S. Posterino and G.D. Lamb in the 2011 issue of this journal. The study confirms the reaction between GSNO and Cys moieties of proteins.
- Subjects
S-nitrosoglutathione; THIOLS; MUSCLE contraction; GLUTATHIONE; PHYSIOLOGICAL research; PROTEIN research
- Publication
Journal of Physiology, 2012, Vol 590, Issue 23, p6247
- ISSN
0022-3751
- Publication type
Article
- DOI
10.1113/jphysiol.2012.237412