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- Title
Recent Developments in the C(sp<sup>3</sup>)−H Functionalization of 2‐Oxindoles through Radical Reactions.
- Authors
Chen, Wei‐ting; Wei, Wen‐ting
- Abstract
Abstract: 3‐Substituted 2‐oxindoles are prevalent in a variety of natural products and bioactive compounds. As such, the synthesis of these molecules is highly desirable. This Focus Review provides a critical overview of recent developments (in particular, reports since 2013) in the C(sp3)−H functionalization of 2‐oxindoles through radical reactions. The main achievements in this field are presented according to the bonds that are formed. Special attention is paid to the reaction mechanisms, and a personal outlook on future developments in this research area is provided.
- Subjects
OXINDOLES; FREE radical reactions; MANNICH reaction; CARBON-carbon bonds; ARYLATION
- Publication
Asian Journal of Organic Chemistry, 2018, Vol 7, Issue 8, p1429
- ISSN
2193-5807
- Publication type
Article
- DOI
10.1002/ajoc.201800209