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- Title
Fluorofuroxans: Synthesis and Application as Photoinduced Nitric Oxide Donors.
- Authors
Ando, Akihiro; Matsubara, Ryosuke; Takazawa, Saori; Shimada, Toshiyuki; Hayashi, Masahiko
- Abstract
The synthesis of 3- and 4-fluorofuroxans is reported for the first time. Under photoirradiation and physiological conditions, 4-fluorofuroxans with weaker nitric oxide-releasing ability are converted into 3-fluorofuroxans, which show remarkable thiol-mediated nitric oxide-releasing properties, thereby suggesting that 4-fluorofuroxans are potent photoinduced nitric oxide donors.
- Subjects
FLUORINE compounds synthesis; FURAZANS; NITRIC oxide
- Publication
Asian Journal of Organic Chemistry, 2016, Vol 5, Issue 7, p886
- ISSN
2193-5807
- Publication type
Article
- DOI
10.1002/ajoc.201600149