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- Title
PENTOSE PHOSPHATE PATHWAY INHIBITION ACTIVATES MACROPHAGES TOWARDS PHAGOCYTIC LYMPHOMA CELL CLEARANCE.
- Authors
Beielstein, A.; Izquierdo‐Alvarez, E.; Blakemore, S.; Nickel, N.; Chawan, S.; Michalik, M.; Brinker, R.; Bartel, H.; Vorholt, D.; Nolte, J.; Linke, R.; Costa Picossi, C. Raissa; Saiz, J.; Villaseñor, A.; Winkels, H.; Hallek, M.; Krueger, M.; Barbas, C.; Pallasch, C.
- Abstract
B Methods: b We addressed macrophage lymphoma cell co-cultures using macrophage cell lines, primary human and murine macrophages, humanized aggressive lymphoma cell model hMB, and primary CLL patient cells. B Introduction: b Treatment response in lymphoma depends on the interaction of macrophages as important effector cells for tumor cell clearance by antibody-dependent cellular phagocytosis (ADCP).
- Subjects
PENTOSE phosphate pathway; MACROPHAGES; LYMPHOMAS
- Publication
Hematological Oncology, 2023, Vol 41, p627
- ISSN
0278-0232
- Publication type
Article
- DOI
10.1002/hon.3165_476