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Single‐Molecule Counting Coupled to Rapid Amplification Enables Detection of α‐Synuclein Aggregates in Cerebrospinal Fluid of Parkinson's Disease Patients.
- Published in:
- Angewandte Chemie, 2021, v. 133, n. 21, p. 11981, doi. 10.1002/ange.202014898
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- Publication type:
- Article
Effect of LRRK2 protein and activity on stimulated cytokines in human monocytes and macrophages.
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- NPJ Parkinson's Disease, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41531-022-00297-9
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- Publication type:
- Article
Parkinson's progression prediction using machine learning and serum cytokines.
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- NPJ Parkinson's Disease, 2019, v. 5, n. 1, p. N.PAG, doi. 10.1038/s41531-019-0086-4
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- Publication type:
- Article
DNA extraction from fresh-frozen and formalin-fixed, paraffinembedded human brain tissue.
- Published in:
- Neuroscience Bulletin, 2013, v. 29, n. 5, p. 649, doi. 10.1007/s12264-013-1379-y
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- Publication type:
- Article
Lipid pathway dysfunction is prevalent in patients with Parkinson's disease.
- Published in:
- 2022
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- Publication type:
- journal article
Reduced LRRK2 in association with retromer dysfunction in post-mortem brain tissue from LRRK2 mutation carriers.
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- 2018
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- Publication type:
- journal article
AMPK-independent pathways regulate skeletal muscle fatty acid oxidation.
- Published in:
- Journal of Physiology, 2008, v. 586, n. 23, p. 5819, doi. 10.1113/jphysiol.2008.159814
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- Publication type:
- Article
Evaluation of plasma levels of NFL, GFAP, UCHL1 and tau as Parkinson's disease biomarkers using multiplexed single molecule counting.
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- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-32480-0
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- Publication type:
- Article
CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK.
- Published in:
- Nature Medicine, 2006, v. 12, n. 5, p. 541, doi. 10.1038/nm1383
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- Publication type:
- Article
Recent Developments in LRRK2-Targeted Therapy for Parkinson's Disease.
- Published in:
- Drugs, 2019, v. 79, n. 10, p. 1037, doi. 10.1007/s40265-019-01139-4
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- Publication type:
- Article
The IkappaB Kinase Family Phosphorylates the Parkinson's Disease Kinase LRRK2 at Ser935 and Ser910 during Toll-Like Receptor Signaling.
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- PLoS ONE, 2012, v. 7, n. 6, p. 1, doi. 10.1371/journal.pone.0039132
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- Publication type:
- Article
WHOPPA Enables Parallel Assessment of Leucine-Rich Repeat Kinase 2 and Glucocerebrosidase Enzymatic Activity in Parkinson’s Disease Monocytes.
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- Frontiers in Cellular Neuroscience, 2022, v. 16, p. 1, doi. 10.3389/fncel.2022.892899
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- Publication type:
- Article
LRRK2 and Lipid Pathways: Implications for Parkinson's Disease.
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- Biomolecules (2218-273X), 2022, v. 12, n. 11, p. 1597, doi. 10.3390/biom12111597
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- Publication type:
- Article
Leucine Rich Repeat Kinase 2 and Innate Immunity.
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- Frontiers in Neuroscience, 2020, p. 1, doi. 10.3389/fnins.2020.00193
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- Publication type:
- Article
Increased unsaturated lipids underlie lipid peroxidation in synucleinopathy brain.
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- Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01469-7
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- Publication type:
- Article
LRRK2 inhibitors and their potential in the treatment of Parkinson's disease: current perspectives.
- Published in:
- Clinical Pharmacology, 2016, v. 8, p. 177, doi. 10.2147/CPAA.S102191
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- Publication type:
- Article
Prediction of motor and non-motor Parkinson's disease symptoms using serum lipidomics and machine learning: a 2-year study.
- Published in:
- NPJ Parkinson's Disease, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41531-024-00741-y
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- Publication type:
- Article
A protective role of ABCA5 in response to elevated sphingomyelin levels in Parkinson's disease.
- Published in:
- NPJ Parkinson's Disease, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41531-024-00632-2
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- Publication type:
- Article
A potential patient stratification biomarker for Parkinson´s disease based on LRRK2 kinase-mediated centrosomal alterations in peripheral blood-derived cells.
- Published in:
- NPJ Parkinson's Disease, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41531-023-00624-8
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- Publication type:
- Article
Editorial: Updates on inflammation in Parkinson's disease.
- Published in:
- Frontiers in Neurology, 2023, v. 14, p. 1, doi. 10.3389/fneur.2023.1138543
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- Publication type:
- Article
Single‐Molecule Counting Coupled to Rapid Amplification Enables Detection of α‐Synuclein Aggregates in Cerebrospinal Fluid of Parkinson's Disease Patients.
- Published in:
- Angewandte Chemie International Edition, 2021, v. 60, n. 21, p. 11874, doi. 10.1002/anie.202014898
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- Publication type:
- Article
Multiple pathways of lipid dysregulation in amyotrophic lateral sclerosis.
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- Brain Communications, 2023, v. 5, n. 1, p. 1, doi. 10.1093/braincomms/fcac340
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- Publication type:
- Article
Sex-specific lipid dysregulation in the Abca7 knockout mouse brain.
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- Brain Communications, 2022, v. 4, n. 3, p. 1, doi. 10.1093/braincomms/fcac120
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- Publication type:
- Article
Mannose 6-Phosphate Receptor Is Reduced in -Synuclein Overexpressing Models of Parkinsons Disease.
- Published in:
- PLoS ONE, 2016, v. 11, n. 8, p. 1, doi. 10.1371/journal.pone.0160501
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- Publication type:
- Article
An emerging role for LRRK2 in the immune system.
- Published in:
- Biochemical Society Transactions, 2012, v. 40, n. 5, p. 1134, doi. 10.1042/BST20120119
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- Publication type:
- Article
Metformin prevents the development of acute lipid-induced insulin resistance in the rat through altered hepatic signaling mechanisms.
- Published in:
- 2004
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- Publication type:
- journal article
Evaluation of Strategies for Measuring Lysosomal Glucocerebrosidase Activity.
- Published in:
- Movement Disorders, 2021, v. 36, n. 12, p. 2719, doi. 10.1002/mds.28815
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- Publication type:
- Article
Cytokines and Gaucher Biomarkers in Glucocerebrosidase Carriers with and Without Parkinson Disease.
- Published in:
- Movement Disorders, 2021, v. 36, n. 6, p. 1451, doi. 10.1002/mds.28525
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- Publication type:
- Article
Cytokines and Gaucher Biomarkers in Glucocerebrosidase Carriers with and Without Parkinson Disease.
- Published in:
- Movement Disorders, 2021, v. 36, n. 6, p. 1451, doi. 10.1002/mds.28525
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- Publication type:
- Article
Toll-like receptor 2 is increased in neurons in Parkinson's disease brain and may contribute to alpha-synuclein pathology.
- Published in:
- Acta Neuropathologica, 2017, v. 133, n. 2, p. 303, doi. 10.1007/s00401-016-1648-8
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- Publication type:
- Article
Reduced glucocerebrosidase activity in monocytes from patients with Parkinson’s disease.
- Published in:
- Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-33921-x
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- Publication type:
- Article
A blood-based marker of mitochondrial DNA damage in Parkinson's disease.
- Published in:
- Science Translational Medicine, 2023, v. 15, n. 711, p. 1, doi. 10.1126/scitranslmed.abo1557
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- Publication type:
- Article
Parkinson's disease-implicated kinases in the brain; insights into disease pathogenesis.
- Published in:
- Frontiers in Molecular Neuroscience, 2014, v. 7, p. 1, doi. 10.3389/fnmol.2014.00057
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- Publication type:
- Article
Characterization of a selective inhibitor of the Parkinson's disease kinase LRRK2.
- Published in:
- Nature Chemical Biology, 2011, v. 7, n. 4, p. 203, doi. 10.1038/nchembio.538
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- Publication type:
- Article
LRRK2-mediated Rab10 phosphorylation in immune cells from Parkinson's disease patients.
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- 2019
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- Publication type:
- journal article
LRRK2 levels and phosphorylation in Parkinson's disease brain and cases with restricted Lewy bodies.
- Published in:
- 2017
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- Publication type:
- journal article
Increased peripheral inflammation in asymptomatic leucine-rich repeat kinase 2 mutation carriers.
- Published in:
- 2016
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- Publication type:
- journal article
Live cell in situ lysosomal GCase activity correlates to alpha-synuclein levels in human differentiated neurons with LRRK2 and GBA1 mutations.
- Published in:
- Frontiers in Cellular Neuroscience, 2023, p. 1, doi. 10.3389/fncel.2023.1229213
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- Publication type:
- Article