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- Title
Imaging in Primary Sjögren's Syndrome.
- Authors
van Ginkel, Martha S.; Glaudemans, Andor W.J.M.; van der Vegt, Bert; Mossel, Esther; Kroese, Frans G.M.; Bootsma, Hendrika; Vissink, Arjan
- Abstract
Primary Sjögren's syndrome (pSS) is a systemic autoimmune disease characterized by dysfunction and lymphocytic infiltration of the salivary and lacrimal glands. Besides the characteristic sicca complaints, pSS patients can present a spectrum of signs and symptoms, which challenges the diagnostic process. Various imaging techniques can be used to assist in the diagnostic work-up and follow-up of pSS patients. Developments in imaging techniques provide new opportunities and perspectives. In this descriptive review, we discuss imaging techniques that are used in pSS with a focus on the salivary glands. The emphasis is on the contribution of these techniques to the diagnosis of pSS, their potential in assessing disease activity and disease progression in pSS, and their contribution to diagnosing and staging of pSS-associated lymphomas. Imaging findings of the salivary glands will be linked to histopathological changes in the salivary glands of pSS patients.
- Subjects
SALIVARY glands; LACRIMAL apparatus; SYMPTOMS
- Publication
Journal of Clinical Medicine, 2020, Vol 9, Issue 8, p2492
- ISSN
2077-0383
- Publication type
Article
- DOI
10.3390/jcm9082492