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- Title
Antihypertensive Drugs and Risk of Cancer: Between Scylla and Charybdis.
- Authors
Sanidas, Elias; Velliou, Maria; Papadopoulos, Dimitrios; Fotsali, Anastasia; Iliopoulos, Dimitrios; Mantzourani, Marina; Toutouzas, Konstantinos; Barbetseas, John
- Abstract
Antihypertensive drugs namely angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, calcium channel blockers, beta blockers, and diuretics are among the most clearly documented regimens worldwide with an overall cardioprotective benefit. Given that malignancy is the second leading cause of mortality, numerous observational studies aimed to investigate the carcinogenic potential of these agents with conflicting results. The purpose of this review was to summarize current data in an effort to explore rare side effects and new mechanisms linking antihypertensive drugs with the risk of developing cancer.
- Subjects
CARCINOGENS; ANTINEOPLASTIC agents; ACE inhibitors; CALCIUM antagonists; ANGIOTENSIN receptors
- Publication
American Journal of Hypertension, 2020, Vol 33, Issue 12, p1049
- ISSN
0895-7061
- Publication type
Article
- DOI
10.1093/ajh/hpaa098