We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Disseminated superficial actinic porokeratosis following hydroxyurea treatment: A case report.
- Authors
Romagnuolo, Maurizio; Riva, Davide; Alberti Violetti, Silvia; Di Benedetto, Alessandra; Barberi, Francesco; Moltrasio, Chiara
- Abstract
Porokeratosis encompass a group of acquired and familial, preneoplastic, keratinization disorders, clinically characterized by atrophic macules or patches with a peripheral keratotic rim, the cornoid lamella. Genetic background is recognized as crucial in its pathophysiology, while immunosuppression and ultraviolet radiation represent triggering factors. We report the case of a woman who developed disseminate superficial actinic porokeratosis following the intake of hydroxyurea for a polycythaemia vera. Clinical, dermoscopic and histopathology data are showed, and the role of drug as a second‐hit mutation trigger is discussed.
- Subjects
HYDROXYUREA; ULTRAVIOLET radiation; MEVALONATE kinase; KERATINIZATION; MACULES
- Publication
Australasian Journal of Dermatology, 2023, Vol 64, Issue 1, pe72
- ISSN
0004-8380
- Publication type
Article
- DOI
10.1111/ajd.13943