We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Sequence variation in the porcinelipoprotein lipasegene.
- Authors
Lei, M. G.; Xiong, Y. Z.; Deng, C. Y.; Wu, Z. F.; Harbitz, I.; Zuo, B.; Dai, L. H.
- Abstract
The article discusses sequence variation in the porcine lipoprotein lipase (LPL) gene. LPL plays a central role in normal lipid metabolism as the key enzyme involved in the hydrolysis of triglycerides present in chylomicrons and very low-density lipoproteins. It mediates fat deposition and mobilization in white adipose tissue in cooperation with hormone-sensitive lipase. The porcine LPL gene has been partially characterized by sequence analysis of a cDNA clone and mapped to chromosome 14 by linkage analysis and in situ hybridization. In this article, the introns 4, 6, 7, 8 of the porcine LPL gene were cloned and sequenced, and a new polymorphism was identified in intron 6.
- Subjects
LIPOPROTEIN lipase; GENES; LIPID metabolism; GENETIC polymorphisms; HYDROLYSIS; TRIGLYCERIDES; ADIPOSE tissues; INTRONS; CHROMOSOMES
- Publication
Animal Genetics, 2004, Vol 35, Issue 5, p422
- ISSN
0268-9146
- Publication type
Article
- DOI
10.1111/j.1365-2052.2004.01185.x