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The sphingosine 1-phosphate receptor 2/4 antagonist JTE-013 elicits off-target effects on sphingolipid metabolism.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-021-04009-w
By:
- Pitman, Melissa R.;
- Lewis, Alexander C.;
- Davies, Lorena T.;
- Moretti, Paul A. B.;
- Anderson, Dovile;
- Creek, Darren J.;
- Powell, Jason A.;
- Pitson, Stuart M.
Publication type:
Article
Systematic Down-Selection of Repurposed Drug Candidates for COVID-19.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 19, p. 11851, doi. 10.3390/ijms231911851
By:
- MacRaild, Christopher A.;
- Mohammed, Muzaffar-Ur-Rehman;
- Faheem;
- Murugesan, Sankaranarayanan;
- Styles, Ian K.;
- Peterson, Amanda L.;
- Kirkpatrick, Carl M. J.;
- Cooper, Matthew A.;
- Palombo, Enzo A.;
- Simpson, Moana M.;
- Jain, Hardik A.;
- Agarwal, Vinti;
- McAuley, Alexander J.;
- Kumar, Anupama;
- Creek, Darren J.;
- Trevaskis, Natalie L.;
- Vasan, Seshadri S.
Publication type:
Article
Retargeting azithromycin analogues to have dual-modality antimalarial activity.
Published in:
BMC Biology, 2020, v. 18, n. 1, p. N.PAG, doi. 10.1186/s12915-020-00859-4
By:
- Burns, Amy L.;
- Sleebs, Brad E.;
- Siddiqui, Ghizal;
- De Paoli, Amanda E.;
- Anderson, Dovile;
- Liffner, Benjamin;
- Harvey, Richard;
- Beeson, James G.;
- Creek, Darren J.;
- Goodman, Christopher D.;
- McFadden, Geoffrey I.;
- Wilson, Danny W.
Publication type:
Article
Multi-omics analysis delineates the distinct functions of sub-cellular acetyl-CoA pools in Toxoplasma gondii.
Published in:
BMC Biology, 2020, v. 18, n. 1, p. 1, doi. 10.1186/s12915-020-00791-7
By:
- Kloehn, Joachim;
- Oppenheim, Rebecca D.;
- Siddiqui, Ghizal;
- De Bock, Pieter-Jan;
- Kumar Dogga, Sunil;
- Coute, Yohann;
- Hakimi, Mohamed-Ali;
- Creek, Darren J.;
- Soldati-Favre, Dominique
Publication type:
Article
Cell biological analysis reveals an essential role for Pfcerli2 in erythrocyte invasion by malaria parasites.
Published in:
Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03020-9
By:
- Liffner, Benjamin;
- Balbin, Juan Miguel;
- Shami, Gerald J.;
- Siddiqui, Ghizal;
- Strauss, Jan;
- Frölich, Sonja;
- Heinemann, Gary K.;
- Edwards, Ella May;
- Alder, Arne;
- Wichers, Jan Stephan;
- Creek, Darren J.;
- Tilley, Leann;
- Dixon, Matthew W. A.;
- Gilberger, Tim-Wolf;
- Wilson, Danny W.
Publication type:
Article
Plasmodium falciparum parasites deploy RhopH2 into the host erythrocyte to obtain nutrients, grow and replicate.
Published in:
eLife, 2017, p. 1, doi. 10.7554/eLife.23217
By:
- Counihan, Natalie A;
- Chisholm, Scott A;
- Bullen, Hayley E;
- Srivastava, Anubhav;
- Sanders, Paul R;
- Jonsdottir, Thorey K.;
- Weiss, Greta E.;
- Ghosh, Sreejoyee;
- Crabb, Brendan S.;
- Creek, Darren J.;
- Gilson, Paul R.;
- De Koning-Ward, Tania F.
Publication type:
Article
Metabolomes and Lipidomes of the Infective Stages of the Gastrointestinal nematodes , Nippostrongylus brasiliensis and Trichuris muris.
Published in:
Metabolites (2218-1989), 2020, v. 10, n. 11, p. 446, doi. 10.3390/metabo10110446
By:
- Yeshi, Karma;
- Creek, Darren J.;
- Anderson, Dovile;
- Ritmejerytė, Edita;
- Becker, Luke;
- Loukas, Alex;
- Wangchuk, Phurpa
Publication type:
Article
Targeting malaria parasites with novel derivatives of azithromycin.
Published in:
Frontiers in Cellular & Infection Microbiology, 2022, v. 12, p. 1, doi. 10.3389/fcimb.2022.1063407
By:
- Burns, Amy L.;
- Sleebs, Brad E.;
- Gancheva, Maria;
- McLean, Kimberley T.;
- Siddiqui, Ghizal;
- Venter, Henrietta;
- Beeson, James G.;
- O’Handley, Ryan;
- Creek, Darren J.;
- Ma, Shutao;
- Frölich, Sonja;
- Goodman, Christopher D.;
- McFadden, Geoffrey I.;
- Wilson, Danny W.
Publication type:
Article
TrypanoCyc: a community-led biochemical pathways database for Trypanosoma brucei.
Published in:
Nucleic Acids Research, 2015, v. 43, n. D1, p. D637, doi. 10.1093/nar/gku944
By:
- Shameer, Sanu;
- Logan-Klumpler, Flora J.;
- Vinson, Florence;
- Cottret, Ludovic;
- Merlet, Benjamin;
- Achcar, Fiona;
- Boshart, Michael;
- Berriman, Matthew;
- Breitling, Rainer;
- Bringaud, Frédéric;
- Bütikofer, Peter;
- Cattanach, Amy M.;
- Bannerman-Chukualim, Bridget;
- Creek, Darren J.;
- Crouch, Kathryn;
- de Koning, Harry P.;
- Denise, Hubert;
- Ebikeme, Charles;
- Fairlamb, Alan H.;
- Ferguson, Michael A. J.
Publication type:
Article
Author Correction: The immune response to RNA suppresses nucleic acid synthesis by limiting ribose 5-phosphate.
Published in:
2024
By:
- Bhattacharjee, Pushpak;
- Wang, Die;
- Anderson, Dovile;
- Buckler, Joshua N;
- de Geus, Eveline;
- Yan, Feng;
- Polekhina, Galina;
- Schittenhelm, Ralf;
- Creek, Darren J;
- Harris, Lawrence D;
- Sadler, Anthony J
Publication type:
Correction Notice
The immune response to RNA suppresses nucleic acid synthesis by limiting ribose 5-phosphate.
Published in:
EMBO Journal, 2024, v. 43, n. 13, p. 2636, doi. 10.1038/s44318-024-00100-w
By:
- Bhattacharjee, Pushpak;
- Wang, Die;
- Anderson, Dovile;
- Buckler, Joshua N;
- de Geus, Eveline;
- Yan, Feng;
- Polekhina, Galina;
- Schittenhelm, Ralf;
- Creek, Darren J;
- Harris, Lawrence D;
- Sadler, Anthony J
Publication type:
Article
Untargeted metabolomics analysis reveals key pathways responsible for the synergistic killing of colistin and doripenem combination against Acinetobacter baumannii.
Published in:
Scientific Reports, 2017, p. 45527, doi. 10.1038/srep45527
By:
- Maifiah, Mohd Hafidz Mahamad;
- Creek, Darren J.;
- Nation, Roger L.;
- Forrest, Alan;
- Tsuji, Brian T.;
- Velkov, Tony;
- Li, Jian
Publication type:
Article
Global metabolic analyses identify key differences in metabolite levels between polymyxin-susceptible and polymyxin-resistant Acinetobacter baumannii.
Published in:
Scientific Reports, 2016, p. 22287, doi. 10.1038/srep22287
By:
- Mahamad Maifiah, Mohd Hafidz;
- Cheah, Soon-Ee;
- Johnson, Matthew D.;
- Han, Mei-Ling;
- Boyce, John D.;
- Thamlikitkul, Visanu;
- Forrest, Alan;
- Kaye, Keith S.;
- Hertzog, Paul;
- Purcell, Anthony W.;
- Song, Jiangning;
- Velkov, Tony;
- Creek, Darren J.;
- Li, Jian
Publication type:
Article
A new mass spectral library for high-coverage and reproducible analysis of the Plasmodium falciparum–infected red blood cell proteome.
Published in:
GigaScience, 2022, v. 11, p. 1, doi. 10.1093/gigascience/giac008
By:
- Siddiqui, Ghizal;
- De Paoli, Amanda;
- MacRaild, Christopher A;
- Sexton, Anna E;
- Boulet, Coralie;
- Shah, Anup D;
- Batty, Mitchell B;
- Schittenhelm, Ralf B;
- Carvalho, Teresa G;
- Creek, Darren J
Publication type:
Article
Plasma Proteome Association and Catalytic Activity of Stealth Polymer-Grafted Iron Oxide Nanoparticles.
Published in:
Small, 2017, v. 13, n. 36, p. n/a, doi. 10.1002/smll.201701528
By:
- Wang, Miaoyi;
- Siddiqui, Ghizal;
- Gustafsson, Ove J. R.;
- Käkinen, Aleksandr;
- Javed, Ibrahim;
- Voelcker, Nicolas H.;
- Creek, Darren J.;
- Ke, Pu Chun;
- Davis, Thomas P.
Publication type:
Article
Sterol 14α-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana.
Published in:
PLoS Neglected Tropical Diseases, 2017, v. 11, n. 6, p. 1, doi. 10.1371/journal.pntd.0005649
By:
- Mwenechanya, Roy;
- Kovářová, Julie;
- Dickens, Nicholas J.;
- Manikhandan, Mudaliar;
- Herzyk, Pawel;
- Vincent, Isabel M.;
- Weidt, Stefan K.;
- Burgess, Karl E.;
- Burchmore, Richard J. S.;
- Pountain, Andrew W.;
- Smith, Terry K.;
- Creek, Darren J.;
- Kim, Dong-Hyun;
- Lepesheva, Galina I.;
- Barrett, Michael P.
Publication type:
Article
Population Pharmacokinetics and Pharmacodynamics of Lumefantrine in Young Ugandan Children Treated With Artemether-Lumefantrine for Uncomplicated Malaria.
Published in:
2016
By:
- Tchaparian, Eskouhie;
- Sambol, Nancy C.;
- Arinaitwe, Emmanuel;
- McCormack, Shelley A.;
- Bigira, Victor;
- Wanzira, Humphrey;
- Muhindo, Mary;
- Creek, Darren J.;
- Sukumar, Nitin;
- Blessborn, Daniel;
- Tappero, Jordan W.;
- Kakuru, Abel;
- Bergqvist, Yngve;
- Aweeka, Francesca T.;
- Parikh, Sunil
Publication type:
journal article
Metabolic Dysregulation Induced in Plasmodium falciparum by Dihydroartemisinin and Other Front-Line Antimalarial Drugs.
Published in:
2016
By:
- Cobbold, Simon A.;
- Chua, Hwa H.;
- Nijagal, Brunda;
- Creek, Darren J.;
- Ralph, Stuart A.;
- McConville, Malcolm J.
Publication type:
journal article
Pharmacokinetic Predictors for Recurrent Malaria After Dihydroartemisinin-Piperaquine Treatment of Uncomplicated Malaria in Ugandan Infants.
Published in:
Journal of Infectious Diseases, 2013, v. 207, n. 11, p. 1646, doi. 10.1093/infdis/jit078
By:
- Creek, Darren J.;
- Bigira, Victor;
- McCormack, Shelley;
- Arinaitwe, Emmanuel;
- Wanzira, Humphrey;
- Kakuru, Abel;
- Tappero, Jordan W.;
- Sandison, Taylor G.;
- Lindegardh, Niklas;
- Nosten, Francois;
- Aweeka, Francesca T.;
- Parikh, Sunil
Publication type:
Article
Cystathionine-β-synthase is essential for AKT-induced senescence and suppresses the development of gastric cancers with PI3K/AKT activation.
Published in:
eLife, 2022, p. 1, doi. 10.7554/eLife.71929
By:
- Haoran Zhu;
- Chan, Keefe T.;
- Xinran Huang;
- Cerra, Carmelo;
- Blake, Shaun;
- Trigos, Anna S.;
- Anderson, Dovile;
- Creek, Darren J.;
- De Souza, David P.;
- Xi Wang;
- Caiyun Fu;
- Jana, Metta;
- Sanij, Elaine;
- Pearson, Richard B.;
- Jian Kang
Publication type:
Article
Genetic and pharmacological evidence for kinetic competition between alternative poly(A) sites in yeast.
Published in:
eLife, 2021, p. 1, doi. 10.7554/eLife.65331
By:
- Turner, Rachael Emily;
- Harrison, Paul F.;
- Swaminathan, Angavai;
- Kraupner-Taylor, Calvin A.;
- Goldie, Belinda J.;
- See, Michael;
- Peterson, Amanda L.;
- Schittenhelm, Ralf B.;
- Powell, David R.;
- Creek, Darren J.;
- Dichtl, Bernhard;
- Beilharz, Traude H.
Publication type:
Article
The 2-methylcitrate cycle is implicated in the detoxification of propionate in Toxoplasma gondii.
Published in:
Molecular Microbiology, 2013, v. 87, n. 4, p. 894, doi. 10.1111/mmi.12139
By:
- Limenitakis, Julien;
- Oppenheim, Rebecca D.;
- Creek, Darren J.;
- Foth, Bernardo J.;
- Barrett, Michael P.;
- Soldati‐Favre, Dominique
Publication type:
Article
Chemoresistant Cancer Cell Lines Are Characterized by Migratory, Amino Acid Metabolism, Protein Catabolism and IFN1 Signalling Perturbations.
Published in:
Cancers, 2022, v. 14, n. 11, p. 2763, doi. 10.3390/cancers14112763
By:
- Acland, Mitchell;
- Lokman, Noor A.;
- Young, Clifford;
- Anderson, Dovile;
- Condina, Mark;
- Desire, Chris;
- Noye, Tannith M.;
- Wang, Wanqi;
- Ricciardelli, Carmela;
- Creek, Darren J.;
- Oehler, Martin K.;
- Hoffmann, Peter;
- Klingler-Hoffmann, Manuela
Publication type:
Article
Benzoxaborole treatment perturbs S-adenosyl-L-methionine metabolism in Trypanosoma brucei.
Published in:
PLoS Neglected Tropical Diseases, 2018, v. 12, n. 5, p. 1, doi. 10.1371/journal.pntd.0006450
By:
- Steketee, Pieter C.;
- Vincent, Isabel M.;
- Achcar, Fiona;
- Giordani, Federica;
- Kim, Dong-Hyun;
- Creek, Darren J.;
- Freund, Yvonne;
- Jacobs, Robert;
- Rattigan, Kevin;
- Horn, David;
- Field, Mark C.;
- MacLeod, Annette;
- Barrett, Michael P.
Publication type:
Article
Integrated metabolomic and transcriptomic analyses of the synergistic effect of polymyxin–rifampicin combination against Pseudomonas aeruginosa.
Published in:
Journal of Biomedical Science, 2022, v. 29, n. 1, p. 1, doi. 10.1186/s12929-022-00874-3
By:
- Mahamad Maifiah, Mohd Hafidz;
- Zhu, Yan;
- Tsuji, Brian T.;
- Creek, Darren J.;
- Velkov, Tony;
- Li, Jian
Publication type:
Article
NormalizeMets: assessing, selecting and implementing statistical methods for normalizing metabolomics data.
Published in:
Metabolomics, 2018, v. 14, n. 5, p. 1, doi. 10.1007/s11306-018-1347-7
By:
- De Livera, Alysha M.;
- Olshansky, Gavriel;
- Simpson, Julie A.;
- Creek, Darren J.
Publication type:
Article
Lipidomics profiles in hepatocytes from nonalcoholic steatohepatitis patients differ markedly from in vitro-induced steatotic hepatocytes.
Published in:
FEBS Letters, 2022, v. 596, n. 11, p. 1445, doi. 10.1002/1873-3468.14318
By:
- Kralj, Thomas;
- Khatri, Raju;
- Brouwer, Kenneth R.;
- Brouwer, Kim L. R.;
- Creek, Darren J.
Publication type:
Article
Mutations in the pantothenate kinase of Plasmodium falciparum confer diverse sensitivity profiles to antiplasmodial pantothenate analogues.
Published in:
PLoS Pathogens, 2018, v. 14, n. 4, p. 1, doi. 10.1371/journal.ppat.1006918
By:
- Tjhin, Erick T.;
- Spry, Christina;
- Sewell, Alan L.;
- Hoegl, Annabelle;
- Barnard, Leanne;
- Sexton, Anna E.;
- Siddiqui, Ghizal;
- Howieson, Vanessa M.;
- Maier, Alexander G.;
- Creek, Darren J.;
- Strauss, Erick;
- Marquez, Rodolfo;
- Auclair, Karine;
- Saliba, Kevin J.
Publication type:
Article
Sulfoxide‐Containing Polymer‐Coated Nanoparticles Demonstrate Minimal Protein Fouling and Improved Blood Circulation.
Published in:
Advanced Science, 2020, v. 7, n. 13, p. 1, doi. 10.1002/advs.202000406
By:
- Qiao, Ruirui;
- Fu, Changkui;
- Li, Yuhuan;
- Qi, Xiaole;
- Ni, Dalong;
- Nandakumar, Aparna;
- Siddiqui, Ghizal;
- Wang, Haiyan;
- Zhang, Zheng;
- Wu, Tingting;
- Zhong, Jian;
- Tang, Shi‐Yang;
- Pan, Shuaijun;
- Zhang, Cheng;
- Whittaker, Michael R.;
- Engle, Jonathan W.;
- Creek, Darren J.;
- Caruso, Frank;
- Ke, Pu Chun;
- Cai, Weibo
Publication type:
Article
Red Blood Cell BCL-x L Is Required for Plasmodium falciparum Survival: Insights into Host-Directed Malaria Therapies.
Published in:
Microorganisms, 2022, v. 10, n. 4, p. N.PAG, doi. 10.3390/microorganisms10040824
By:
- Boulet, Coralie;
- Siddiqui, Ghizal;
- Gaynor, Taylah L.;
- Doerig, Christian;
- Creek, Darren J.;
- Carvalho, Teresa G.
Publication type:
Article
Chemoproteomics validates selective targeting of Plasmodium M1 alanyl aminopeptidase as an antimalarial strategy.
Published in:
eLife, 2024, p. 1, doi. 10.7554/eLife.92990
By:
- Giannangelo, Carlo;
- Challis, Matthew P.;
- Siddiqui, Ghizal;
- Edgar, Rebecca;
- Malcolm, Tess R.;
- Webb, Chaille T.;
- Drinkwater, Nyssa;
- Vinh, Natalie;
- Macraild, Christopher;
- Counihan, Natalie;
- Duffy, Sandra;
- Wittlin, Sergio;
- Devine, Shane M.;
- Avery, Vicky M.;
- De Koning-Ward, Tania;
- Scammells, Peter;
- McGowan, Sheena;
- Creek, Darren J.
Publication type:
Article
Non‐canonical metabolic pathways in the malaria parasite detected by isotope‐tracing metabolomics.
Published in:
Molecular Systems Biology, 2021, v. 17, n. 4, p. 1, doi. 10.15252/msb.202010023
By:
- Cobbold, Simon A;
- V Tutor, Madel;
- Frasse, Philip;
- McHugh, Emma;
- Karnthaler, Markus;
- Creek, Darren J;
- Odom John, Audrey;
- Tilley, Leann;
- Ralph, Stuart A;
- McConville, Malcolm J
Publication type:
Article
A high parasite density environment induces transcriptional changes and cell death in <italic>Plasmodium falciparum</italic> blood stages.
Published in:
FEBS Journal, 2018, v. 285, n. 5, p. 848, doi. 10.1111/febs.14370
By:
- Chou, Evelyn S.;
- Abidi, Sabia Z.;
- Teye, Marian;
- Leliwa‐Sytek, Aleksandra;
- Rask, Thomas S.;
- Cobbold, Simon A.;
- Tonkin‐Hill, Gerry Q.;
- Subramaniam, Krishanthi S.;
- Sexton, Anna E.;
- Creek, Darren J.;
- Daily, Johanna P.;
- Duffy, Michael F.;
- Day, Karen P.
Publication type:
Article
Anthelmintic closantel enhances bacterial killing of polymyxin B against multidrug-resistant Acinetobacter baumannii.
Published in:
Journal of Antibiotics, 2016, v. 69, n. 6, p. 415, doi. 10.1038/ja.2015.127
By:
- Tran, Thien B;
- Cheah, Soon-Ee;
- Yu, Heidi H;
- Bergen, Phillip J;
- Nation, Roger L;
- Creek, Darren J;
- Purcell, Anthony;
- Forrest, Alan;
- Doi, Yohei;
- Song, Jiangning;
- Velkov, Tony;
- Li, Jian
Publication type:
Article
Host Reticulocytes Provide Metabolic Reservoirs That Can Be Exploited by Malaria Parasites.
Published in:
PLoS Pathogens, 2015, v. 11, n. 6, p. 1, doi. 10.1371/journal.ppat.1004882
By:
- Srivastava, Anubhav;
- Creek, Darren J.;
- Evans, Krystal J.;
- De Souza, David;
- Schofield, Louis;
- Müller, Sylke;
- Barrett, Michael P.;
- McConville, Malcolm J.;
- Waters, Andrew P.
Publication type:
Article
Probing the Metabolic Network in Bloodstream-Form Trypanosoma brucei Using Untargeted Metabolomics with Stable Isotope Labelled Glucose.
Published in:
PLoS Pathogens, 2015, v. 11, n. 3, p. 1, doi. 10.1371/journal.ppat.1004689
By:
- Creek, Darren J.;
- Mazet, Muriel;
- Achcar, Fiona;
- Anderson, Jana;
- Kim, Dong-Hyun;
- Kamour, Ruwida;
- Morand, Pauline;
- Millerioux, Yoann;
- Biran, Marc;
- Kerkhoven, Eduard J.;
- Chokkathukalam, Achuthanunni;
- Weidt, Stefan K.;
- Burgess, Karl E. V.;
- Breitling, Rainer;
- Watson, David G.;
- Bringaud, Frédéric;
- Barrett, Michael P.
Publication type:
Article
BCKDH: The Missing Link in Apicomplexan Mitochondrial Metabolism Is Required for Full Virulence of Toxoplasma gondii and Plasmodium berghei.
Published in:
PLoS Pathogens, 2014, v. 10, n. 7, p. 1, doi. 10.1371/journal.ppat.1004263
By:
- Oppenheim, Rebecca D.;
- Creek, Darren J.;
- Macrae, James I.;
- Modrzynska, Katarzyna K.;
- Pino, Paco;
- Limenitakis, Julien;
- Polonais, Valerie;
- Seeber, Frank;
- Barrett, Michael P.;
- Billker, Oliver;
- McConville, Malcolm J.;
- Soldati-Favre, Dominique
Publication type:
Article
Genetic and chemical validation of Plasmodium falciparum aminopeptidase PfA-M17 as a drug target in the hemoglobin digestion pathway.
Published in:
eLife, 2022, p. 1, doi. 10.7554/eLife.80813
By:
- Edgar, Rebecca C. S.;
- Siddiqui, Ghizal;
- Hjerrild, Katheryn;
- Malcolm, Tess R.;
- Vinh, Natalie B.;
- Webb, Chaille T.;
- Holmes, Clare;
- MacRaild, Christopher A.;
- Chernih, Hope C.;
- Suen, Willy W.;
- Counihan, Natalie A.;
- Creek, Darren J.;
- Scammells, Peter J.;
- McGowan, Sheena;
- de Koning-Ward, Tania F.
Publication type:
Article
Comparative Metabolomics Reveals Key Pathways Associated With the Synergistic Killing of Colistin and Sulbactam Combination Against Multidrug-Resistant Acinetobacter baumannii.
Published in:
Frontiers in Pharmacology, 2019, p. 1, doi. 10.3389/fphar.2019.00754
By:
- Han, Mei-Ling;
- Liu, Xiaofen;
- Velkov, Tony;
- Lin, Yu-Wei;
- Zhu, Yan;
- Creek, Darren J.;
- Barlow, Christopher K.;
- Yu, Heidi H.;
- Zhou, Zhihui;
- Zhang, Jing;
- Li, Jian
Publication type:
Article
Synergistic Killing of Polymyxin B in Combination With the Antineoplastic Drug Mitotane Against Polymyxin-Susceptible and -Resistant Acinetobacter baumannii: A Metabolomic Study.
Published in:
Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00359
By:
- Tran, Thien B.;
- Bergen, Phillip J.;
- Creek, Darren J.;
- Velkov, Tony;
- Li, Jian
Publication type:
Article
Stage-Specific Changes in Plasmodium Metabolism Required for Differentiation and Adaptation to Different Host and Vector Environments.
Published in:
PLoS Pathogens, 2016, v. 12, n. 12, p. 1, doi. 10.1371/journal.ppat.1006094
By:
- Srivastava, Anubhav;
- Philip, Nisha;
- Hughes, Katie R.;
- Georgiou, Konstantina;
- MacRae, James I.;
- Barrett, Michael P.;
- Creek, Darren J.;
- McConville, Malcolm J.;
- Waters, Andrew P.
Publication type:
Article
Benznidazole Biotransformation and Multiple Targets in Trypanosoma cruzi Revealed by Metabolomics.
Published in:
PLoS Neglected Tropical Diseases, 2014, v. 8, n. 5, p. 1, doi. 10.1371/journal.pntd.0002844
By:
- Trochine, Andrea;
- Creek, Darren J.;
- Faral-Tello, Paula;
- Barrett, Michael P.;
- Robello, Carlos
Publication type:
Article
Benznidazole Biotransformation and Multiple Targets in Trypanosoma cruzi Revealed by Metabolomics.
Published in:
PLoS Neglected Tropical Diseases, 2014, v. 8, n. 5, p. 1, doi. 10.1371/journal.pntd.0002844
By:
- Trochine, Andrea;
- Creek, Darren J.;
- Faral-Tello, Paula;
- Barrett, Michael P.;
- Robello, Carlos
Publication type:
Article
Untargeted Metabolomics Reveals a Lack Of Synergy between Nifurtimox and Eflornithine against Trypanosoma brucei.
Published in:
PLoS Neglected Tropical Diseases, 2012, v. 6, n. 5, p. 1, doi. 10.1371/journal.pntd.0001618
By:
- Vincent, Isabel M.;
- Creek, Darren J.;
- Burgess, Karl;
- Woods, Debra J.;
- Burchmore, Richard J. S.;
- Barrett, Michael P.
Publication type:
Article
Measuring Sulforaphane and Its Metabolites in Human Plasma: A High Throughput Method.
Published in:
Molecules, 2020, v. 25, n. 4, p. 829, doi. 10.3390/molecules25040829
By:
- Langston-Cox, Annie;
- Anderson, Dovile;
- Creek, Darren J.;
- Palmer, Kirsten;
- Wallace, Euan M.;
- Marshall, Sarah A.
Publication type:
Article
Bio‐Mimicking Brain Vasculature to Investigate the Role of Heterogeneous Shear Stress in Regulating Barrier Integrity.
Published in:
Advanced Biology, 2022, v. 6, n. 12, p. 1, doi. 10.1002/adbi.202200152
By:
- Mehta, Ami;
- Desai, Anal;
- Rudd, David;
- Siddiqui, Ghizal;
- Nowell, Cameron J.;
- Tong, Ziqiu;
- Creek, Darren J.;
- Tayalia, Prakriti;
- Gandhi, Prasanna S.;
- Voelcker, Nicolas H.
Publication type:
Article
Multi-omics Based Identification of Specific Biochemical Changes Associated With PfKelch13-Mutant Artemisinin-Resistant Plasmodium falciparum.
Published in:
2017
By:
- Siddiqui, Ghizal;
- Srivastava, Anubhav;
- Russell, Adrian S.;
- Creek, Darren J.
Publication type:
journal article
Global Gene Expression Profile of Acinetobacter baumannii During Bacteremia.
Published in:
2017
By:
- Murray, Gerald L.;
- Kostoulias, Xenia P.;
- Boyce, John D.;
- Peleg, Anton Y.;
- Tsyganov, Kirill;
- Powell, David;
- Bulach, Dieter M.;
- Creek, Darren J.;
- Paulsen, Ian T.
Publication type:
journal article
System-wide biochemical analysis reveals ozonide antimalarials initially act by disrupting Plasmodium falciparum haemoglobin digestion.
Published in:
PLoS Pathogens, 2020, v. 16, n. 6, p. 1, doi. 10.1371/journal.ppat.1008485
By:
- Giannangelo, Carlo;
- Siddiqui, Ghizal;
- De Paoli, Amanda;
- Anderson, Bethany M.;
- Edgington-Mitchell, Laura E.;
- Charman, Susan A.;
- Creek, Darren J.
Publication type:
Article
Analytical and Omics-Based Advances in the Study of Drug-Induced Liver Injury.
Published in:
Toxicological Sciences, 2021, v. 183, n. 1, p. 1, doi. 10.1093/toxsci/kfab069
By:
- Kralj, Thomas;
- Brouwer, Kim L R;
- Creek, Darren J
Publication type:
Article

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