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TGF-β signal shifting between tumor suppression and fibro-carcinogenesis in human chronic liver diseases.
Published in:
2014
By:
- Matsuzaki, Koichi;
- Seki, Toshihito;
- Okazaki, Kazuichi
Publication type:
journal article
TGF-β signal shifting between tumor suppression and fibro-carcinogenesis in human chronic liver diseases.
Published in:
Journal of Gastroenterology, 2014, v. 49, n. 6, p. 971, doi. 10.1007/s00535-013-0910-2
By:
- Matsuzaki, Koichi;
- Seki, Toshihito;
- Okazaki, Kazuichi
Publication type:
Article
Relevance of the Core 70 and IL-28B polymorphism and response-guided therapy of peginterferon alfa-2a ± ribavirin for chronic hepatitis C of Genotype 1b: a multicenter randomized trial, ReGIT-J study.
Published in:
2014
By:
- Nishiguchi, Shuhei;
- Enomoto, Hirayuki;
- Aizawa, Nobuhiro;
- Nishikawa, Hiroki;
- Osaki, Yukio;
- Tsuda, Yasuhiro;
- Higuchi, Kazuhide;
- Okazaki, Kazuichi;
- Seki, Toshihito;
- Kim, Soo Ryang;
- Hongo, Yasushi;
- Jyomura, Hisato;
- Nishida, Naoshi;
- Kudo, Masatoshi
Publication type:
journal article
Relevance of the Core 70 and IL-28B polymorphism and response-guided therapy of peginterferon alfa-2a ± ribavirin for chronic hepatitis C of Genotype 1b: a multicenter randomized trial, ReGIT-J study.
Published in:
Journal of Gastroenterology, 2014, v. 49, n. 3, p. 492, doi. 10.1007/s00535-013-0785-2
By:
- Nishiguchi, Shuhei;
- Enomoto, Hirayuki;
- Aizawa, Nobuhiro;
- Nishikawa, Hiroki;
- Osaki, Yukio;
- Tsuda, Yasuhiro;
- Higuchi, Kazuhide;
- Okazaki, Kazuichi;
- Seki, Toshihito;
- Kim, Soo;
- Hongo, Yasushi;
- Jyomura, Hisato;
- Nishida, Naoshi;
- Kudo, Masatoshi
Publication type:
Article
Percutaneous Microwave Coagulation Therapy for Solitary Metastatic Liver Tumors From Colorectal Cancer: A Pilot Clinical Study.
Published in:
American Journal of Gastroenterology (Springer Nature), 1999, v. 94, n. 2, p. 322, doi. 10.1111/j.1572-0241.1999.00849.x
By:
- Seki, Toshihito;
- Wakabayashi, Masayuki;
- Nakagawa, Taiichi;
- Imamura, Masato;
- Tamai, Toru;
- Nishimura, Akira;
- Yamashiki, Noriyo;
- Inoue, Kyoichi
Publication type:
Article
A Case of Hilar Cholangiocarcinoma Treated by Microwave Tissue Coagulation Therapy via Percutaneous Transhepatic Choledochoscopy.
Published in:
1990
By:
- Seki, Toshihito;
- Kubota, Yoshitsugu;
- Kunieda, Kouji;
- Nakatani, Sei;
- Mizuno, Takako;
- Sameshima, Yoshiko
Publication type:
Letter
Ultrasonically Guided Percutaneous Ethanol Injection Therapy for Hepatocellular Carcinoma.
Published in:
American Journal of Gastroenterology (Springer Nature), 1989, v. 84, n. 11, p. 1400
By:
- Seki, Toshihito;
- Nonaka, Tsuneyuki;
- Kubota, Yoshitsugu;
- Mizuno, Takako;
- Sameshima, Yoshiko
Publication type:
Article
Benign Strictures of the Intrahepatic Bile Ducts Managed with Percutaneous Transhepatic Cholangioscopy: A Case Report.
Published in:
Digestive Endoscopy, 1990, v. 2, n. 4, p. 402, doi. 10.1111/j.1443-1661.1990.tb00071.x
By:
- KUBOTA, Yoshitsugu;
- SEKI, Toshihito;
- YAMAGUCHI, Takashi;
- KUNIEDA, Kouji;
- TANI, Kazuhiro;
- KIN, Hideyuki;
- MIZUNO, Takako;
- SAMESHIMA, Yoshiko
Publication type:
Article
Long-term Efficacy of Percutaneous Transhepatic Choledochoscopic Y AG Laser Therapy for Malignant Biliary Obstruction.
Published in:
Digestive Endoscopy, 1990, v. 2, n. 2, p. 156, doi. 10.1111/j.1443-1661.1990.tb00336.x
By:
- KUBOTA, Yoshitsugu;
- SEKI, Toshihito;
- KUNIEDA, Kouji;
- NAKAHASHI, Yoshitsugu;
- YAMAGUCHI, Takashi;
- TATEIWA, Jiro;
- MIZUNO, Takako;
- SHIOZAKI, Yasuko;
- SAMESHIMA, Yoshiko
Publication type:
Article
Hepatocellular Carcinoma in Child-Pugh C Cirrhosis: Prognostic Factors and Survival Benefit of Nontransplant Treatments.
Published in:
Digestive Diseases, 2013, v. 31, n. 5/6, p. 490, doi. 10.1159/000355259
By:
- Kudo, Masatoshi;
- Osaki, Yukio;
- Matsunaga, Takashi;
- Kasugai, Hiroshi;
- Oka, Hiroko;
- Seki, Toshihito
Publication type:
Article
Phosphorylated Smad2 and Smad3 signaling: Shifting between tumor suppression and fibro-carcinogenesis in chronic hepatitis C.
Published in:
Hepatology Research, 2013, v. 43, n. 12, p. 1327, doi. 10.1111/hepr.12082
By:
- Yamaguchi, Takashi;
- Matsuzaki, Koichi;
- Inokuchi, Ryosuke;
- Kawamura, Rinako;
- Yoshida, Katsunori;
- Murata, Miki;
- Fujisawa, Junichi;
- Fukushima, Nobuyoshi;
- Sata, Michio;
- Kage, Masayoshi;
- Nakashima, Osamu;
- Tamori, Akihiro;
- Kawada, Norifumi;
- Tsuneyama, Koichi;
- Dooley, Steven;
- Seki, Toshihito;
- Okazaki, Kazuichi
Publication type:
Article
Effects of late evening snack including branched-chain amino acid on the function of hepatic parenchymal cells in patients with liver cirrhosis.
Published in:
Hepatology Research, 2011, v. 41, n. 5, p. 417, doi. 10.1111/j.1872-034X.2011.00795.x
By:
- Koreeda, Chizu;
- Seki, Toshihito;
- Okazaki, Kazuichi;
- Ha-Kawa, Sang Kil;
- Sawada, Satoshi
Publication type:
Article
A proposal of the modified liver damage classification for hepatocellular carcinoma
Published in:
Hepatology Research, 2006, v. 34, n. 2, p. 124, doi. 10.1016/j.hepres.2005.10.009
By:
- Chung, Hobyung;
- Kudo, Masatoshi;
- Haji, Seiji;
- Osaki, Yukio;
- Oka, Hiroko;
- Seki, Toshihito;
- Kasugai, Hiroshi;
- Sasaki, Yo
Publication type:
Article
Multidrug resistance3 is in situ detected in the liver of patients with primary biliary cirrhosis, and induced in human hepatoma cells by bezafibrate
Published in:
Hepatology Research, 2004, v. 30, n. 3, p. 125, doi. 10.1016/j.hepres.2004.08.015
By:
- Matsumoto, Takayuki;
- Miyazaki, Hiroaki;
- Nakahashi, Yoshitsugu;
- Hirohara, Junko;
- Seki, Toshihito;
- Inoue, Kyoichi;
- Okazaki, Kazuichi
Publication type:
Article
Viral Infection in Esophageal, Gastric, and Colorectal Cancer.
Published in:
Healthcare (2227-9032), 2022, v. 10, n. 9, p. 1626, doi. 10.3390/healthcare10091626
By:
- Yamashina, Takeshi;
- Shimatani, Masaaki;
- Takeo, Masahiro;
- Sasaki, Kotaro;
- Orino, Masahiro;
- Saito, Natsuko;
- Matsumoto, Hironao;
- Kasai, Takeshi;
- Kano, Masataka;
- Horitani, Shunsuke;
- Sumimoto, Kimi;
- Mitsuyama, Toshiyuki;
- Yuba, Takafumi;
- Seki, Toshihito;
- Naganuma, Makoto
Publication type:
Article
TGF-ßand HGF transmit the signals through JNK-dependent Smad2/3 phosphorylation at the linker regions.
Published in:
Oncogene, 2004, v. 23, n. 44, p. 7416, doi. 10.1038/sj.onc.1207981
By:
- Mori, Shigeo;
- Matsuzaki, Koichi;
- Yoshida, Katsunori;
- Furukawa, Fukiko;
- Tahashi, Yoshiya;
- Yamagata, Hideo;
- Sekimoto, Go;
- Seki, Toshihito;
- Matsui, Hirofumi;
- Nishizawa, Mikio;
- Fujisawa, Jun-Ichi;
- Okazaki, Kazuichi
Publication type:
Article
Smad Phospho-Isoforms for Hepatocellular Carcinoma Risk Assessment in Patients with Nonalcoholic Steatohepatitis.
Published in:
Cancers, 2020, v. 12, n. 2, p. 286, doi. 10.3390/cancers12020286
By:
- Suwa, Kanehiko;
- Yamaguchi, Takashi;
- Yoshida, Katsunori;
- Murata, Miki;
- Ichimura, Mayuko;
- Tsuneyama, Koichi;
- Seki, Toshihito;
- Okazaki, Kazuichi
Publication type:
Article
Gel Immersion Endoscopic Mucosal Resection (EMR) for Superficial Nonampullary Duodenal Epithelial Tumors May Reduce Procedure Time Compared with Underwater EMR (with Video).
Published in:
Gastroenterology Research & Practice, 2022, p. 1, doi. 10.1155/2022/2040792
By:
- Yamashina, Takeshi;
- Shimatani, Masaaki;
- Takahashi, Yu;
- Takeo, Masahiro;
- Saito, Natsuko;
- Matsumoto, Hironao;
- Kasai, Takeshi;
- Kano, Masataka;
- Sumimoto, Kimi;
- Mitsuyama, Toshiyuki;
- Marusawa, Hiroyuki;
- Nishio, Akiyoshi;
- Yuba, Takafumi;
- Seki, Toshihito;
- Naganuma, Makoto
Publication type:
Article
Percutaneous microwave coagulation therapy for patients with small hepatocellular carcinoma.
Published in:
Cancer (0008543X), 1999, v. 85, n. 8, p. 1694, doi. 10.1002/(SICI)1097-0142(19990415)85:8<1694::AID-CNCR8>3.0.CO;2-3
By:
- Seki, Toshihito;
- Wakabayashi, Masayuki;
- Nakagawa, Taiichi;
- Imamura, Masato;
- Tamai, Toru;
- Nishimura, Akira;
- Yamashiki, Noriyo;
- Okamura, Akiharu;
- Inoue, Kyoichi
Publication type:
Article
Lewis Y antigen expression in hepatocellular carcinoma. An immunohistochemical study.
Published in:
1995
By:
- Wakabayashi, Masayuki;
- Shiro, Tomohiro;
- Seki, Toshihito;
- Nakagawa, Taiichi;
- Itoh, Takayuki;
- Imamura, Masato;
- Shiozaki, Yasuko;
- Inoue, Kyoichi;
- Okamura, Akiharu;
- Wakabayashi, M;
- Shiro, T;
- Seki, T;
- Nakagawa, T;
- Itoh, T;
- Imamura, M;
- Shiozaki, Y;
- Inoue, K;
- Okamura, A
Publication type:
journal article
Ultrasonically guided percutaneous microwave coagulation therapy for small hepatocellular carcinoma.
Published in:
1994
By:
- Seki, Toshihito;
- Wakabayashi, Masayuki;
- Nakagawa, Taiichi;
- Itho, Takayuki;
- Shiro, Tomohiro;
- Kunieda, Kouji;
- Sato, Masahiro;
- Uchiyama, Syouzou;
- Inoue, Kyoichi;
- Seki, T;
- Wakabayashi, M;
- Nakagawa, T;
- Itho, T;
- Shiro, T;
- Kunieda, K;
- Sato, M;
- Uchiyama, S;
- Inoue, K
Publication type:
journal article
A correlation of argyrophilic nucleolar organizer regions with stages of hepatocellular carcinoma.
Published in:
1993
By:
- Shiro, Tomohiro;
- Seki, Toshihito;
- Naitoh, Yuji;
- Inoue, Kyoichi;
- Okamura, Akiharu;
- Shiro, T;
- Seki, T;
- Naitoh, Y;
- Inoue, K;
- Okamura, A
Publication type:
journal article
A randomized phase II trial of intra-arterial chemotherapy using SM-11355 (Miriplatin) for hepatocellular carcinoma.
Published in:
Investigational New Drugs, 2012, v. 30, n. 5, p. 2015, doi. 10.1007/s10637-011-9776-4
By:
- Okusaka, Takuji;
- Kasugai, Hiroshi;
- Ishii, Hiroshi;
- Kudo, Masatoshi;
- Sata, Michio;
- Tanaka, Katsuaki;
- Shioyama, Yasukazu;
- Chayama, Kazuaki;
- Kumada, Hiromitsu;
- Yoshikawa, Masaharu;
- Seki, Toshihito;
- Saito, Hidetugu;
- Hayashi, Naoaki;
- Shiratori, Keiko;
- Okita, Kiwamu;
- Sakaida, Isao;
- Honda, Masao;
- Kusumoto, Yukio;
- Tsutsumi, Takuya;
- Sakata, Kenji
Publication type:
Article
Combination therapy with transcatheter arterial chemoembolization and percutaneous microwave coagulation therapy for hepatocellular carcinoma.
Published in:
Cancer (0008543X), 2000, v. 89, n. 6, p. 1245, doi. 10.1002/1097-0142(20000915)89:6<1245::AID-CNCR8>3.0.CO;2-F
By:
- Seki, Toshihito;
- Tamai, Toru;
- Nakagawa, Taiichi;
- Imamura, Masato;
- Nishimura, Akira;
- Yamashiki, Noriyo;
- Ikeda, Kozo;
- Inoue, Kyoichi
Publication type:
Article
Acute necrotizing pancreatitis as a fatal complication following DC Bead transcatheter arterial chemoembolization for hepatocellular carcinoma: A case report and review of the literature.
Published in:
Molecular & Clinical Oncology, 2018, v. 9, n. 4, p. 403, doi. 10.3892/mco.2018.1690
By:
- Yamaguchi, Takashi;
- Seki, Toshihito;
- Komemushi, Atsushi;
- Suwa, Kanehiko;
- Tsuda, Rinako;
- Inokuchi, Ryosuke;
- Murata, Miki;
- Yuki, Michiko;
- Harima, Yoko;
- Okazaki, Kazuichi
Publication type:
Article
S-1 monotherapy in a patient with cholangiolocellular carcinoma: A case report.
Published in:
2016
By:
- TAKASHI YAMAGUCHI;
- TOSHIHITO SEKI;
- RYOSUKE INOKUCHI;
- RINAKO KAWAMURA;
- MIKI MURATA;
- KOICHI MATSUZAKI;
- OSAMU NAKASHIMA;
- TSUTOMU KUMABE;
- KAZUICHI OKAZAKI
Publication type:
Case Study
A Prospective Randomized Controlled Trial of Preoperative Whole-Liver Chemolipiodolization for Hepatocellular Carcinoma.
Published in:
Digestive Diseases & Sciences, 2012, v. 57, n. 5, p. 1404, doi. 10.1007/s10620-012-2029-3
By:
- Kaibori, Masaki;
- Tanigawa, Noboru;
- Kariya, Shuji;
- Ikeda, Hiroki;
- Nakahashi, Yoshitsugu;
- Hirohara, Junko;
- Koreeda, Chizu;
- Seki, Toshihito;
- Sawada, Satoshi;
- Okazaki, Kazuichi;
- Kwon, A-Hon
Publication type:
Article
Cutaneous and Colonic Metastases After Resection of Hepatocellular Carcinoma.
Published in:
Digestive Diseases & Sciences, 2007, v. 52, n. 4, p. 1114, doi. 10.1007/s10620-006-9465-x
By:
- Masaki Kaibori;
- Mika Morita;
- Shuuji Tagami;
- Yoichiro Uchida;
- Hironori Tanaka;
- Kazuhiko Yoshioka;
- Yu Takahashi;
- Noriko Sakaida;
- Yoshiko Uemura;
- Toshihito Seki;
- Kazuichi Okazaki;
- Yasuo Kamiyama
Publication type:
Article
Combined Treatment of Large Hepatocellular Carcinoma with Transcatheter Arterial Chemoembolization and Percutaneous Ethanol Injection with a Multipronged Needle: Experimental and Clinical Investigation.
Published in:
CardioVascular & Interventional Radiology, 2012, v. 35, n. 2, p. 325, doi. 10.1007/s00270-011-0184-0
By:
- Kawamura, Rinako;
- Seki, Toshihito;
- Umehara, Hideto;
- Ikeda, Kozo;
- Inokuchi, Ryosuke;
- Asayama, Toshiki;
- Yamaguchi, Takashi;
- Takahashi, Yu;
- Sakao, Masayuki;
- Lencioni, Riccardo;
- Okazaki, Kazuichi
Publication type:
Article
Efficacy of microwave ablation versus radiofrequency ablation for hepatocellular carcinoma: a propensity score analysis.
Published in:
Abdominal Radiology, 2021, v. 46, n. 8, p. 3790, doi. 10.1007/s00261-021-03008-9
By:
- Suwa, Kanehiko;
- Seki, Toshihito;
- Aoi, Kazunori;
- Yamashina, Masao;
- Murata, Miki;
- Yamashiki, Noriyo;
- Nishio, Akiyoshi;
- Shimatani, Masaaki;
- Naganuma, Makoto
Publication type:
Article
Surgical Control of a Primary Hepatic Carcinoid Tumor: A Case Report.
Published in:
Case Reports in Gastroenterology, 2009, v. 3, n. 1, p. 30, doi. 10.1159/000208375
By:
- Yokoigawa, Norio;
- Kitade, Hiroaki;
- Ohishi, Masaharu;
- Ozaki, Takashi;
- Miyaso, Takeshi;
- Okazaki, Satoshi;
- Nakai, Koji;
- Yoshida, Ryo;
- Imada, Seiki;
- Imamura, Atsushi;
- Kawaguchi, Yusai;
- Takada, Hideho;
- Shikata, Nobuaki;
- Seki, Toshihito;
- Kwon, A.-H.
Publication type:
Article
A New Prognostic Staging System for Hepatocellular Carcinoma: Value of the Biomarker Combined Japan Integrated Staging Score.
Published in:
Intervirology, 2008, v. 51, p. 86, doi. 10.1159/000122599
By:
- Kitai, Satoshi;
- Kudo, Masatoshi;
- Minami, Yasunori;
- Ueshima, Kazuomi;
- Hobyung Chung;
- Hagiwara, Satoru;
- Inoue, Tatsuo;
- Ishikawa, Emi;
- Takahashi, Shunsuke;
- Asakuma, Yutaka;
- Haji, Seiji;
- Osaki, Yukio;
- Oka, Hiroko;
- Seki, Toshihito;
- Kasugai, Hiroshi;
- Sasaki, Yo;
- Matsunaga, Takashi
Publication type:
Article
Validation of a New Prognostic Staging System for Hepatocellular Carcinoma: A Comparison of the Biomarker-Combined Japan Integrated Staging Score, the Conventional Japan Integrated Staging Score and the BALAD Score.
Published in:
Oncology, 2008, v. 75, p. 83, doi. 10.1159/000173428
By:
- Kitai, Satoshi;
- Kudo, Masatoshi;
- Minami, Yasunori;
- Haji, Seiji;
- Osaki, Yukio;
- Oka, Hiroko;
- Seki, Toshihito;
- Kasugai, Hiroshi;
- Sasaki, Yo;
- Matsunaga, Takashi
Publication type:
Article
Severe Complications of Radiofrequency Ablation Therapy for Hepatocellular Carcinoma: An Analysis of 3,891 Ablations in 2,614 Patients.
Published in:
Oncology, 2007, v. 72, p. 72, doi. 10.1159/000111710
By:
- Kasugai, Hiroshi;
- Osaki, Yukio;
- Oka, Hiroko;
- Kudo, Masatoshi;
- Seki, Toshihito
Publication type:
Article
Interstitial pneumonia induced by sorafenib in a patient with hepatocellular carcinoma: An autopsy case report.
Published in:
Oncology Letters, 2015, v. 9, n. 4, p. 1633, doi. 10.3892/ol.2015.2934
By:
- TAKASHI YAMAGUCHI;
- TOSHIHITO SEKI;
- CHIKA MIYASAKA;
- RYOSUKE INOKUCHI;
- RINAKO KAWAMURA;
- YUUTAKU SAKAGUCHI;
- MIKI MURATA;
- KOICHI MATSUZAKI;
- YORIKA NAKANO;
- YOSHIKO UEMURA;
- KAZUICHI OKAZAKI
Publication type:
Article
Short term treatment results of local ablation with water-cooled microwave antenna for liver cancer: Comparison with radiofrequency ablation.
Published in:
Molecular & Clinical Oncology, 2020, v. 12, n. 3, p. 230, doi. 10.3892/mco.2020.1983
By:
- Suwa, Kanehiko;
- Seki, Toshihito;
- Tsuda, Rinako;
- Yamashina, Masao;
- Murata, Miki;
- Yamaguchi, Takashi;
- Nishio, Akiyoshi;
- Okazaki, Kazuichi
Publication type:
Article
Multicenter prospective analysis of newly diagnosed hepatocellular carcinoma with respect to the percentage of Lens culinaris agglutinin-reactive α-fetoprotein<sup>1</sup>.
Published in:
Journal of Gastroenterology & Hepatology, 2001, v. 16, n. 12, p. 1378, doi. 10.1046/j.1440-1746.2001.02643.x
By:
- Oka, Hiroko;
- Saito, Akiko;
- Ito, Kazuki;
- Kumada, Takashi;
- Satomura, Shinji;
- Kasugai, Hiroshi;
- Osaki, Yukio;
- Seki, Toshihito;
- Kudo, Masatoshi;
- Tanaka, Masatoshi
Publication type:
Article
Histopathological changes after microwave coagulation therapy for patients with hepatocellular carcinoma: review of 15 explanted livers
Published in:
American Journal of Gastroenterology (Springer Nature), 2003, v. 98, n. 9, p. 2052, doi. 10.1111/j.1572-0241.2003.07642.x
By:
- Yamashiki, Noriyo;
- Kato, Tomoaki;
- Bejarano, Pablo A.;
- Berho, Mariana;
- Montalvo, Berta;
- Shebert, Robert T.;
- Goodman, Zachary D.;
- Seki, Toshihito;
- Schiff, Eugene R.;
- Tzakis, Andreas G.
Publication type:
Article

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