We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Effectiveness and Tolerability of Colesevelam HCl for Accelerated Elimination of Teriflunomide in Healthy Participants.
- Authors
Lunven, Catherine; Guo, Zuyu; Turpault, Sandrine; Delfolie, Astrid; Fauchoux, Nicolas; Turner, Timothy; Baldinetti, Francesca
- Abstract
The article presents a study using the accelerated elimination procedure (AEP) which reduces the plasma concentrations of the oral immunomodulator teriflunomide. It discusses the adverse events while using teriflunomide in case of pregnancy, and analyze the safety of the bile acid sequestrant Colesevelam hydrochloride (HCl) and pharmacokinetic (PK) parameters of teriflunomide.
- Subjects
DRUG tolerance; PHARMACOKINETICS; DRUG therapy; IMMUNOLOGICAL adjuvants; MEDICAL protocols
- Publication
Journal of Clinical Pharmacology, 2017, Vol 57, Issue 6, p747
- ISSN
0091-2700
- Publication type
Article
- DOI
10.1002/jcph.854