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- Title
Acute respiratory distress syndrome due to exposure to high-concentration mixture of ethenone and crotonaldehyde.
- Authors
Huang, Jun-Feng; Zhu, Du-Ming; Ma, Jie-Fei; Zhong, Ming
- Abstract
Introduction: Acute inhalational exposure leads to rapidly progressive acute respiratory distress syndrome (ARDS). This report is the first one to present a patient with ARDS in relation to long-standing exposure to a high-concentration mixture of ethenone and crotonaldehyde. Case report: A male worker in a chemical plant was accidentally exposed to the mixture of high-concentrated ethenone and crotonaldehyde for 5 min in an open space and worked continuously in the polluted area for approximately 12 h. On admission, he was conscious with the following vital parameters: blood pressure, 151/91 mmHg; pulse rate, 107 beats/min; respiratory rate, 30 breaths/min; temperature, 37.6°C; oxygen saturation, 92% supported by mask saturation 10 L/min; arterial blood gases showed P/F oxygen ratio of less than 200. Physical examination disclosed decreased bilateral vesicular sounds. A chest computed tomography revealed bilateral nonsegmental ground-glass opacities. The patient was mechanically ventilated and treated with corticosteroid. The patient was discharged without any symptoms. Conclusion: Exposure to mixtures of ethenone and crotonaldehyde can cause severe pulmonary injury leading to delayed ARDS.
- Subjects
RESPIRATORY distress syndrome; CROTONALDEHYDE; PARAMETER estimation; COMPUTED tomography; SYMPTOMS
- Publication
Toxicology & Industrial Health, 2015, Vol 31, Issue 7, p585
- ISSN
0748-2337
- Publication type
Article
- DOI
10.1177/0748233713480205