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- Title
Safety of Cold Snare Polypectomy in Patients Receiving Treatment with Antithrombotic Agents.
- Authors
Arimoto, Jun; Chiba, Hideyuki; Ashikari, Keiichi; Fukui, Ryo; Anan, Hideyuki; Tachikawa, Jun; Suto, Takuma; Kawano, Naoya; Niikura, Toshihiro; Kuwabara, Hiroki; Nakaoka, Michiko; Kato, Shingo; Ida, Tomonori; Morohashi, Taiki; Goto, Tohru; Nakajima, Atsushi
- Abstract
<bold>Background: </bold>With the aging of the population and rising incidence of thromboembolic events, the clinical use of antithrombotic agents is also increasing. There are few reports yet on the management of antithrombotic agent use in patients undergoing cold snare polypectomy (CSP).<bold>Aims: </bold>The aim of this study was to evaluate whether continued administration of antithrombotic agents in patients undergoing CSP would be associated with an increased rate of delayed post-polypectomy bleeding (DPPB).<bold>Methods: </bold>A total of 1177 colorectal polyps in 501 patients were resected at Omori Red Cross Hospital between October 2017 and March 2018. The polyps were divided into two groups depending on whether the patients received antithrombotic agent treatment or not: the antithrombotic group (911 polyps) and the no-antithrombotic group (266 polyps).<bold>Results: </bold>Among the 1177 polyp resections, there was no case of DPPB, including in the antithrombotic group. Immediate bleeding occurred in a total of 63 (5.4%) cases. Polyp location in the rectum (OR (95% CI) 2.64 (1.223-5.679); p = 0.013), polyp size ≥ 6 mm (OR (95% CI) 4.64 (2.719-7.933); p < 0.001), polypoid growth pattern (OR (95% CI) 2.78 (1.607-4.793); p < 0.001), and antithrombotic agent use (OR (95% CI) 2.98 (1.715-5.183); p < 0.001) were identified as significant risk factors of immediate bleeding.<bold>Conclusions: </bold>Continued use of antithrombotic agents does not increase the risk of DPPB, even in those receiving multiple antithrombotic agents. Thus, it is safe to perform CSP even in multiple agent users. Prospective, randomized studies are necessary to confirm our results.
- Subjects
FIBRINOLYTIC agents; POLYPECTOMY; COLON polyps; PATIENT safety; HEMORRHAGE
- Publication
Digestive Diseases & Sciences, 2019, Vol 64, Issue 11, p3247
- ISSN
0163-2116
- Publication type
journal article
- DOI
10.1007/s10620-019-5469-1