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- Title
Ictal hypoventilation contributes to cardiac arrhythmia and SUDEP: Report on two deaths in video-EEG–monitored patients.
- Authors
Bateman, Lisa M.; Spitz, Mark; Seyal, Masud
- Abstract
Sudden unexplained death in epilepsy (SUDEP) is a common cause of death in patients with epilepsy, with cardiorespiratory dysfunction and a primary cessation of cerebral function proposed as causes. We report two cases of SUDEP in patients with intractable temporal lobe epilepsy undergoing video-EEG (electroencephalography) telemetry at two centers. Both had secondarily generalized convulsions. EEG, electrocardiography (ECG), and respiratory changes in these two patients are reported herein. Ictal/postictal hypoventilation may contribute to SUDEP with the resulting hypoxemia and acidosis leading to failure of recovery of cortical function and eventual cardiac failure.
- Subjects
SUDDEN death; EPILEPSY; ARRHYTHMIA; SPASMS; DEVELOPMENTAL disabilities
- Publication
Epilepsia (Series 4), 2010, Vol 51, Issue 5, p916
- ISSN
0013-9580
- Publication type
Article
- DOI
10.1111/j.1528-1167.2009.02513.x