We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
A study of Serum Vitamin D and Vaspin Levels among patients with Acute Myocardial Infraction.
- Authors
Samala, Shravan Kumar; Akul, Kolanuri; Tabassum, Majida; Shishtla, Pratibha Gayatri
- Abstract
Background : Acute Myocardial Infarction (AMI) is a major cause of morbidity and mortality worldwide. Emerging evidence suggests that vitamin D deficiency and adipokines like vaspin play significant roles in the pathophysiology of cardiovascular diseases. However, the relationship between serum vitamin D levels, vaspin levels, and AMI remains poorly understood. Aim and Objectives : To evaluate and compare serum vitamin D and vaspin levels in patients with AMI and healthy individuals. Materials and Method : This cross-sectional study involved 100 participants, divided into two groups: 50 patients diagnosed with AMI and 50 age- and sex-matched healthy controls. Serum levels of vitamin D and vaspin were measured using enzyme-linked immunosorbent assay (ELISA) techniques. Clinical and demographic data were collected and analyzed. Statistical analysis was performed to compare serum levels between the two groups and to evaluate the correlation between vitamin D and vaspin levels. Results : The results showed that serum vitamin D levels were significantly lower in AMI patients compared to controls (p<0.05). Conversely, serum vaspin levels were significantly higher in the AMI group (p<0.05). Conclusion : The study concludes that lower vitamin D levels and elevated vaspin levels are associated with AMI. These biomarkers may serve as potential predictors for the risk and severity of AMI, offering new insights into the pathogenesis and potential therapeutic targets for cardiovascular disease management. Further research is warranted to explore the underlying mechanisms and clinical implications.
- Subjects
CARDIOVASCULAR diseases risk factors; VITAMIN D; MYOCARDIAL infarction; VITAMIN D deficiency; ENZYME-linked immunosorbent assay; CARDIOVASCULAR diseases
- Publication
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research), 2024, Vol 15, Issue 8, p1675
- ISSN
0975-3583
- Publication type
Article