We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Factors Associated With Hepatitis A Seropositivity at 23 Years After Childhood Vaccination.
- Authors
Scobie, Heather M; Negus, Susan; Stevenson, Timothy; Bressler, Sara; Bruden, Dana; Simons, Brenna C; Snowball, Mary; Hofmeister, Megan G; Bruce, Michael; Townshend-Bulson, Lisa; Fischer, Marc; McMahon, Brian
- Abstract
We evaluated factors associated with the presence of hepatitis A virus antibodies 23 years after initiating vaccination at ages 6–15 months. Among 67 participants, 86% (42/49) of those vaccinated at ages 12–15 months and 61% (11/18) of those vaccinated at 6 months remained seropositive at 23 years. Lack of maternal antibodies at enrollment and higher initial vaccine response were independently associated with higher antibody concentrations at 23 years. Further research is needed to assess the duration of hepatitis A vaccine protection and possible need for a booster dose.
- Subjects
VACCINATION of children; BOOSTER vaccines; VACCINE effectiveness; VIRAL antibodies; HEPATITIS viruses
- Publication
Open Forum Infectious Diseases, 2024, Vol 11, Issue 7, p1
- ISSN
2328-8957
- Publication type
Article
- DOI
10.1093/ofid/ofae417