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- Title
Diagnosis of Helicobacter pylori infection.
- Authors
Tonkic, Ante; Vukovic, Jonatan; Vrebalov Cindro, Pavle; Pesutic Pisac, Valdi; Tonkic, Marija
- Abstract
Helicobacter pylori infections represent an important factor in the pathogenesis of chronic gastritis, peptic ulcer, MALT lymphoma and gastric adenocarcinoma. The recently published Maastricht V/Florence consensus report indicated that the urea breath test using 13 C urea still remains the best non-invasive test to diagnose H. pylori infections with high sensitivity and specificity. Among the stool antigen tests, the ELISA monoclonal antibody test is a rational option. Effective therapy should be based only on susceptibility testing in regions with documented high clarithromycin resistance (>15%). Advanced high-resolution endoscopic technologies enable increased diagnostic accuracy for detection of H. pylori infections.
- Subjects
HELICOBACTER pylori infections; ENZYME-linked immunosorbent assay; MONOCLONAL antibodies; GASTRITIS; MUCOSA-associated lymphoid tissue lymphoma; DIAGNOSIS
- Publication
Wiener Klinische Wochenschrift, 2018, Vol 130, Issue 17/18, p530
- ISSN
0043-5325
- Publication type
Article
- DOI
10.1007/s00508-018-1356-6