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- Title
Aβ induces oxidative stress in senescence-accelerated (SAMP8) mice.
- Authors
Kurara Takagane; Jun Nojima; Hiroaki Mitsuhashi; Satoshi Suo; Dai Yanagihara; Fumio Takaiwa; Yasuomi Urano; Noriko Noguchi; Shoichi Ishiura
- Abstract
The article discusses a study which aimed to establish the relationship between oxidative stress and amyloid B (AB) in Alzheimer's disease (AD) by injecting rice AB vaccine to senescence-accelerated (SAMP8) mice model. Topics discussed include quantification of the anti-AB antibody titer by enzyme-linked immunosorbent assay (ELISA), a behavioral test in Y-maze, and the Western blotting of insoluble fractions.
- Subjects
OXIDATIVE stress; AMYLOID beta-protein; ALZHEIMER'S disease research; ANIMAL models for aging; IMMUNOGLOBULINS
- Publication
Bioscience, Biotechnology & Biochemistry, 2015, Vol 79, Issue 6, p912
- ISSN
0916-8451
- Publication type
Article
- DOI
10.1080/09168451.2014.1002449