We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Electrochemical C−H/N−H Functionalization for the Synthesis of Highly Functionalized (Aza)indoles.
- Authors
Hou, Zhong ‐ Wei; Mao, Zhong ‐ Yi; Zhao, Huai ‐ Bo; Melcamu, Yared Yohannes; Lu, Xin; Song, Jinshuai; Xu, Hai ‐ Chao
- Abstract
Indoles and azaindoles are among the most important heterocycles because of their prevalence in nature and their broad utility in pharmaceutical industry. Reported herein is an unprecedented noble-metal- and oxidant-free electrochemical method for the coupling of (hetero)arylamines with tethered alkynes to synthesize highly functionalized indoles, as well as the more challenging azaindoles.
- Subjects
ELECTROCHEMICAL analysis; AZAINDOLES; HETEROCYCLIC compounds synthesis; COUPLING reactions (Chemistry); ALKYNES; AROMATIC amines
- Publication
Angewandte Chemie, 2016, Vol 128, Issue 32, p9314
- ISSN
0044-8249
- Publication type
Article
- DOI
10.1002/ange.201602616