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- Title
Electrical stimulation compared with tolterodine for treatment of urge/urge incontinence amongst women-a randomized controlled trial.
- Authors
Franzén, Karin; Johansson, Jan-Erik; Lauridsen, Inger; Canelid, Jill; Heiwall, Bengt; Nilsson, Kerstin
- Abstract
Introduction and hypothesis: Few randomized controlled trials have compared electrical stimulation treatment with drug therapy. Our hypothesis was that electrical stimulation treatment in women with urgency/urge incontinence would be more efficient compared to drug treatment. Methods: Women ≥18 years of age with urgency/urge incontinence were randomized to receive either ten electrical stimulation treatments vaginally and transanally over a period of 5-7 weeks or tolterodine 4 mg orally once daily. Results: Sixty-one women completed the study. There was no significant difference between the two treatment groups in micturition rate from baseline to 6 months, mean difference, −0.40 (95% confidence interval (CI), −1.61 to 0.82), but a clearly significant difference within each group for electrical stimulation, −2.8 (95% CI, −3.7 to −1.9), and for tolterodine, −3.2 (95% CI, −4.1 to −2.4). Conclusions: Both treatments reduced the number of micturitions, but electrical stimulation was not found to be superior to tolterodine.
- Subjects
ELECTRIC stimulation; DRUG therapy; URINATION; CLINICAL trials; FEMALE reproductive organ diseases; GENITOURINARY diseases; STATISTICAL tolerance regions; RANDOMIZED controlled trials
- Publication
International Urogynecology Journal, 2010, Vol 21, Issue 12, p1517
- ISSN
0937-3462
- Publication type
Article
- DOI
10.1007/s00192-010-1213-2