We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
The impact of sporotrichosis in HIV-infected patients: a systematic review.
- Authors
Moreira, José; Freitas, Dayvison; Lamas, Cristiane
- Abstract
Sporotrichosis is a fungal infection of man and animals caused by Sporothrix complex. It usually presents as a lymphocutaneous form, but disseminated disease may occur. Given the paucity of data about HIV/AIDS and sporotrichosis co-infection, a systematic review of reported cases of HIV-associated sporotrichosis found via Pubmed (1984-2013) was done. A total of 39 papers were included, and 58 patients' data analyzed. Thirty-three (56.9 %) cases were from Brazil and 18 (31 %) from the USA. Patients' mean age was 37.8 ± 10.4 years; males predominated (84.5 %). The median CD4 cell count was 97 cells/mm. The most common clinical forms were disseminated and disseminated cutaneous with 33 (56.9 %) and 10 (17.5 %) patients, respectively. There was a correlation between CD4 count and clinical categories ( p = 0.002). Mortality was 30 % and there was a correlation between central nervous system involvement and death ( p < 0.001).
- Subjects
HIV infections; HIV-positive persons; MEDLINE; ONLINE information services; PROBABILITY theory; SPOROTRICHOSIS; STATISTICAL hypothesis testing; SURVIVAL analysis (Biometry); SYSTEMATIC reviews; COMORBIDITY; HIGHLY active antiretroviral therapy; TREATMENT effectiveness; DATA analysis software; CD4 lymphocyte count; KRUSKAL-Wallis Test
- Publication
Infection, 2015, Vol 43, Issue 3, p267
- ISSN
0300-8126
- Publication type
Article
- DOI
10.1007/s15010-015-0746-1