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- Title
Genetic analysis of four porcine avian influenza viruses isolated from Shandong, China.
- Authors
Shi, W. F.; Gibbs, M. J.; Zhang, Y. Z.; Zhang, Z.; Zhao, X. M.; Jin, X.; Zhu, C. D.; Yang, M. F.; Yang, N. N.; Cui, Y. J.; Ji, L.
- Abstract
A Bayesian phylogenetic analysis of eight separate gene segments indicated A/Swine/Shandong/2/2003 (H5N1), A/Swine/Shandong/na/2003 (H9N2), A/Swine/Shandong/nb/2003 (H9N2) and A/Swine/Shandong/nc/2005 (H9N2) probably represent two multiple reassortant lineages, that had not been described before, with genes coming from H5N1, H9N2 and other lineages from poultry in Asia. Amino acid motifs within the haemagglutinin sequence of A/Swine/Shandong/nb/2003 suggested it may be able to infect people, whereas the sequences of the other three isolates suggested they would not have had that capability. Our analysis emphasizes the need for a comprehensive study of the interactions between H5N1 and H9N2 viruses in Asia that includes sequencing and phylogenetic investigation.
- Subjects
ASIA; AVIAN influenza; PHYLOGENY; SWINE; AMINO acids
- Publication
Archives of Virology, 2008, Vol 153, Issue 1, p211
- ISSN
0304-8608
- Publication type
Report
- DOI
10.1007/s00705-007-1083-1