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- Title
Successful Treatment with Paclitaxel/Carboplatin Chemotherapy in Advanced Adenocarcinoma of the Urinary Tract Producing Carcinoembryonic Antigen, Carbohydrate Antigen 19-9 and Carbohydrate Antigen 125.
- Authors
Kato, Manabu; Onishi, Takehisa; Hoshina, Akira; Yabana, Tadasihi
- Abstract
Primary adenocarcinoma of the urinary tract producing tumor markers is extremely rare. We report 2 cases of advanced adenocarcinoma of the urinary tract producing carcinoembryonic antigen (CEA), carbohydrate antigen 19-9 (CA19-9) and carbohydrate antigen 125 (CA125), which were completely resected after induction chemotherapy with paclitaxel and carboplatin. Patient 1 was a 72-year-old woman with adenocarcinoma of the right renal pelvis and ureter. Patient 2 was a 73-year-old woman with adenocarcinoma of the bladder. Serum levels of CEA, CA19-9 and CA125 were extremely elevated in both cases. They were successfully treated with paclitaxel puls carboplatin followed by surgery. Both patients were proved to have achieved pathological complete regression by surgical specimens and have been alive without recurrence for more than 18 and 6 months, respectively. Copyright © 2010 S. Karger AG, Basel
- Subjects
ADENOCARCINOMA; URINARY organ diseases; TUMORS; CARCINOEMBRYONIC antigen; URETER diseases; PACLITAXEL
- Publication
Urologia Internationalis, 2010, Vol 84, Issue 1, p116
- ISSN
0042-1138
- Publication type
Article
- DOI
10.1159/000273479