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- Title
Three cases of difficulty in achieving definitive loss of consciousness with remimazolam.
- Authors
Miyanishi, Mao; Yaguramaki, Toru; Maehara, Yasuhiro; Nagata, Osamu
- Abstract
Background: Remimazolam is a novel, ultra-short-acting benzodiazepine used for general anesthesia. Because remimazolam is an emerging drug, the tolerance to remimazolam in benzodiazepine-taking patients has been unclear. Also, the efficacy of remimazolam in different races is not fully elucidated so far. Case presentation: Here we experienced three cases in which high dose of remimazolam was needed for attempting to achieve appropriate anesthetic depth. Two of the three cases were of preoperatively benzodiazepine-taking patients. The other was a case of a Chinese patient. In all three cases, conversion to general anesthesia with propofol was necessitated. Conclusions: When signs of inadequate sedative effect of remimazolam are observed in patients of benzodiazepine users or of different races, conversion to another sedative agent such as propofol should be considered.
- Subjects
LOSS of consciousness; GENERAL anesthesia; PROPOFOL; SEDATIVES
- Publication
JA Clinical Reports, 2022, Vol 8, Issue 1, p1
- ISSN
2363-9024
- Publication type
Article
- DOI
10.1186/s40981-021-00485-1