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- Title
Microwave Assisted Synthesis and Antimicrobial Activity of Novel Pyrrolidine Derivatives.
- Authors
Sreekanth, K.; Jha, Anjali
- Abstract
Microwave assisted synthesis of 1-acetyl-2-benzylpyrrolidine-2-carboxylic acid and its derivatives has been developed with highly encouraging yields. 2-Benzyl-tert-butylpyrrolidine-1,2-dicarboxylate is used as an initial compound in the four steps synthesis of the target compounds. Structures of the products 5a–5h have been confirmed by spectroscopic methods. According to antimicrobial tests 1-acetyl-2-benzylpyrrolidine-2-carboxamide 5c is determined to be the most potent product.
- Subjects
PYRROLIDINE; MICROWAVES; ACID derivatives
- Publication
Russian Journal of General Chemistry, 2020, Vol 90, Issue 1, p129
- ISSN
1070-3632
- Publication type
Article
- DOI
10.1134/S107036322001020X