We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Translating Anti-Inflammatory Strategies for Atherosclerosis: Deep Phenotyping, Next-Generation Drug Targets, and Precision Medicine.
- Authors
Asare, Yaw; Georgakis, Marios K.
- Abstract
Atherosclerosis, a condition characterized by inflammation in the arteries, is the main cause of cardiovascular disease (CVD), including heart attacks and strokes. While current treatments focus on lowering cholesterol levels, new anti-inflammatory strategies are being explored as potential therapies for atherosclerosis. These strategies involve targeting the immune system's role in atherosclerosis and have shown promise in reducing CVD risk. However, challenges such as the risk of infections and individual variability in drug response need to be addressed. Advances in technologies like single-cell transcriptomics and PET imaging are aiding in the deeper understanding of the immune landscape of atherosclerosis and the identification of potential drug targets and biomarkers. These developments may lead to personalized therapies for atherosclerosis in the future.
- Subjects
REGULATORY T cells; MAJOR adverse cardiovascular events; ATHEROSCLEROTIC plaque; CARDIOVASCULAR system; POSITRON emission tomography; METABOLOMICS
- Publication
Cells (2073-4409), 2024, Vol 13, Issue 15, p1306
- ISSN
2073-4409
- Publication type
Article
- DOI
10.3390/cells13151306