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- Title
Non-dipping phenomenon in children with monosymptomatic nocturnal enuresis.
- Authors
Kahraman, Aydin; Dursun, Hasan; Hatipoglu, Sami; Kural, Bahar; Sahin, Mustafa; Birgul, Korhan; Akyol, Mehmet
- Abstract
Purpose: Monosymptomatic nocturnal enuresis is a common disorder seen in childhood, and many factors play a role in its etiopathology to varying degrees. The aim of our study was to investigate the possible association between nocturnal enuresis and 24-h blood pressure profiles of enuretic children. Methods: A total of 45 children ranging in age from 6 to 15 years with monosymptomatic nocturnal enuresis and 22 age-matched healthy controls were enrolled in our study. The blood pressure measurement was made at 30-min intervals during a 24-h period via an ambulatory blood pressure measurement device. Both groups underwent medical tests that included a complete blood count, blood biochemistry profile, urinalysis and blood renin-aldosterone levels, and all study subjects received an abdominal ultrasound. Results: Statistically significant high nocturnal blood pressure levels were observed in our patients with monosymptomatic nocturnal enuresis compared with the control group ( p < 0.05). The mean values of the day-to-night difference (dipping) in the systolic and diastolic blood pressure of the patients were significantly lower than those of control group ( p < 0.05). Conclusion: Nocturnal enuresis should not only be accepted as a urinary system disorder. Possible systemic causative factors have to be examined, especially in patients that are resistant to first-line therapy. Based on the results of our study, we deduce that one of the factors that plays a role in the pathogenesis of enuresis nocturna is a non-dipping blood pressure profile (the 'non-dipping' phenomenon).
- Subjects
TURKEY; ACADEMIC medical centers; AMBULATORY blood pressure monitoring; BLOOD pressure; CHI-squared test; STATISTICAL correlation; ENURESIS; T-test (Statistics); DATA analysis software; DESCRIPTIVE statistics
- Publication
Pediatric Nephrology, 2013, Vol 28, Issue 7, p1099
- ISSN
0931-041X
- Publication type
Article
- DOI
10.1007/s00467-013-2448-1