We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Jak2 is involved in c-Myc induction by Bcr-Abl.
- Authors
Shanhai Xie; Hui Lin; Tong Sun; Arlinghaus, Ralph B.
- Abstract
Presents a study that investigated the involvement of Jak2 tyrosine kinase in c-Myc protein induction by inducing c-Myc mRNA expression. Background on the induction of c-Myc requires Bcr-Abl positive cell tyrosine kinase activity; Inhibition of Jak2 tyrosine activity blocks c-Myc induction by Bcr-Abl; Details on the treatment of cells with a Jak2 kinase inhibitor.
- Subjects
PROTEIN-tyrosine kinases; CELLS; MESSENGER RNA
- Publication
Oncogene, 2002, Vol 21, Issue 47, p7137
- ISSN
0950-9232
- Publication type
Article
- DOI
10.1038/sj.onc.1205942