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- Title
Frailty in multiple sclerosis: A closer look at the deficit accumulation framework.
- Authors
Zanotto, Tobia; Lynch, Sharon G; Hausdorff, Jeffrey M; Sosnoff, Jacob J
- Abstract
Given the complex, multi-factorial pathophysiology of MS, there is perhaps a need to better understand which and how many domains of function (and relative weight of health deficits) should be considered to design a valid FI in MS populations. While many approaches to conceptualize and evaluate frailty exist, the frailty index (FI), based on the deficit accumulation framework,[1] has often appealed to clinicians due to its adaptability and utility in routine care. The growing availability and effectiveness of disease-modifying therapies has increased the life expectancy of people living with multiple sclerosis (MS).
- Subjects
FRAILTY; MULTIPLE sclerosis
- Publication
Multiple Sclerosis Journal, 2022, Vol 28, Issue 6, p1000
- ISSN
1352-4585
- Publication type
Letter
- DOI
10.1177/13524585211061332