We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Fatal underhanded chronic enterovirus infection associated with anti-CD20 monotherapy for central nervous system demyelinating disease.
- Authors
Luciani, Léa; Ninove, Laetitia; Zandotti, Christine; Chalvignac, Virginie; Lagier, David; Baume, Julien; Mélade, Julien; Piorkowski, Géraldine; Coutard, Bruno; Lepidi, Hubert; Pelletier, Jean; Audoin, Bertrand; Rico-Lamy, Audrey; Nougairède, Antoine
- Abstract
We report a fatal case of coxsackievirus B4 chronic infection in a 30-year-old woman with a diagnosis of myelin oligodendrocyte glycoprotein antibody-associated disorder controlled by rituximab monotherapy for 3 years. Initially presenting as self-limited meningitis, the infection remained silent for 8 months before the sudden onset of fulminant myocarditis. Analysis of the complete genome showed that the same virus was responsible for both episodes.
- Subjects
CENTRAL nervous system diseases; ENTEROVIRUS diseases; MYELIN sheath diseases; MYELIN oligodendrocyte glycoprotein; DIAGNOSIS
- Publication
Multiple Sclerosis Journal, 2021, Vol 27, Issue 2, p320
- ISSN
1352-4585
- Publication type
Article
- DOI
10.1177/1352458520923978