We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Genetická analýza z krvi matky.
- Authors
Sysák, Rastislav; Štencl, Peter; Vlková, Barbora Izrael; Greksová, Katarína; Oroszová, Viera; Hrebenár, Marcel
- Abstract
It has been 16 years since there has been a discovery of cell-free fetal DNA (cffDNA) in mother's blood. However in the last 5 years there has been more researching done in the purpose of its specific diagnosis, concentration and molecular size, which have later on reflected into particular tests. These have been available only in the past 2 years. Within the actual trend in preference of non-invasive methods of prenatal diagnosis and its shifting into first trimester the examination of mother's blood has been showing as a very perspective method for early cell-free fetal DNA discovering of chromosome aberration diagnosis of fetus. Its wider enforcement is unfortunatelly limited by a small amount of studies within non-risk pregnancy groups of patients as well as its higher financial cost. Despite of this information this method is extending further more from United States of America into whole world which lowers its costs and its becoming more accesible for a wider amount of patients. Within detailed researching in a group of risk pregnancy patients this method could perspectively minimize a risk of fetus loss which is main complication of invasive methods of prenatal diagnosis.
- Subjects
PRENATAL diagnosis; DIAGNOSIS of fetal diseases; FETAL cells from maternal blood; HUMAN chromosome abnormality diagnosis; DIAGNOSIS of Down syndrome
- Publication
Actual Gynecology & Obstetrics / Aktuální Gynekologie a Porodnictví, 2014, Vol 6, p1
- ISSN
1803-9588
- Publication type
Article