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- Title
ROLE OF HUMAN PAPILLOMA VIRUS IN ORAL CARCINOMA AND POTENTIALLY MALIGNANT DISORDERS OF THE ORAL CAVITY.
- Authors
Boparai, Arshdeep Kaur; Arora, Preeti Chawla; Singh Boparai, Chetan Dev; Cheema, Gursimran Kaur; Singh, Balwinder
- Abstract
Human Papillomavirus (HPV) as an etiologic factor in the development of oral cancer and potentially malignant disorders continues to be a debated topic. The etiology of head and neck malignancies is multiphasic and multifactorial. Tobacco and alcohol consumption are the most common risk factors for head and neck malignancy. Other factors, including DNA viruses, especially human papilloma virus (HPV), may also play a role in the development of these lesions. Number of studies have been conducted over the past two decades to prove whether the HPV infection could have a role in the oral carcinoma carcinogenesis. HPV was first established as cancer development agent in cervical cancer. The prevalence of HPV in benign lesions as well as malignancies has been assessed by many techniques. Among these, the polymerase chain reaction is the most sensitive method. The role of HPV in etiopathogenesis of oral carcinoma and potentially malignant disorders of the oral cavity is briefly reviewed here.
- Subjects
PAPILLOMAVIRUS diseases; DNA virus diseases; CARCINOMA; CARCINOMA in situ; CHORDOMA
- Publication
Indian Journal of Comprehensive Dental Care (IJCDC), 2015, Vol 5, Issue 1, p583
- ISSN
2231-6973
- Publication type
Article