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- Title
Constant Quest for Quality: Digital Cytopathology.
- Authors
Van Es, Simone L.; Greaves, Janelle; Gay, Stephanie; Ross, Jennifer; Holzhauser, Derek; Badrick, Tony
- Abstract
Background: Special consideration should be given when creating and selecting cytopathology specimens for digitization to maximize quality. Advances in scanning and viewing technology can also improve whole-slide imaging (WSI) output quality. Methods: Accumulated laboratory experience with digitization of glass cytopathology slides was collected. Results: This paper describes characteristics of a cytopathology glass slide that can reduce quality on resulting WSI. Important points in the glass cytopathology slide selection process, preparation, scanning, and WSI-editing process that will maximize the quality of the resulting acquired digital image are covered. The paper outlines scanning solutions which have potential to predict issues with a glass cytopathology slide before image acquisition, allowing for adjustment of the scanning approach. WSI viewing solutions that better simulate the traditional microscope experience are also discussed. Conclusion: In addition to taking advantage of technical advances, practical steps can taken to maximize quality of cytopathology WSI.
- Subjects
CELLULAR pathology; QUALITY assurance; VIRTUAL microscopy
- Publication
Journal of Pathology Informatics, 2018, Vol 9, p1
- ISSN
2229-5089
- Publication type
Article
- DOI
10.4103/jpi.jpi_6_18