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- Title
Exploring the Association between Delirium and Malnutrition in COVID-19 Survivors: A Geriatric Perspective.
- Authors
Damanti, Sarah; Cilla, Marta; Vitali, Giordano; Tiraferri, Valeria; Pomaranzi, Chiara; De Rubertis, Giulia; De Lorenzo, Rebecca; Di Lucca, Giuseppe; Scotti, Raffaella; Messina, Emanuela; Dell'Acqua, Raffaele; Guffanti, Monica; Cinque, Paola; Castagna, Antonella; Rovere-Querini, Patrizia; Tresoldi, Moreno
- Abstract
Older individuals face an elevated risk of developing geriatric syndromes when confronted with acute stressors like COVID-19. We assessed the connection between in-hospital delirium, malnutrition, and frailty in a cohort of COVID-19 survivors. Patients aged ≥65, hospitalized in a tertiary hospital in Milan for SARS-CoV-2 pneumonia, were enrolled and screened for in-hospital delirium with the 4 'A's Test (4AT) performed twice daily (morning and evening) during hospital stay. Malnutrition was assessed with the malnutrition universal screening tool (MUST) at hospital admission and with the mini-nutritional assessment short-form (MNA-SF) one month after hospital discharge. Frailty was computed with the frailty index one month after hospital discharge. Fifty patients (median age 78.5, 56% male) were enrolled. At hospital admission, 10% were malnourished. The 13 patients (26%) who developed delirium were frailer (7 vs. 4), experienced a higher in-hospital mortality (5 vs. 3), and were more malnourished one month after discharge (3 of the 4 patients with delirium vs. 6 of the 28 patients without delirium who presented at follow up). The 4AT scores correlated with the MNA-SF scores (r = −0.55, p = 0.006) and frailty (r = 0.35, p = 0.001). Frailty also correlated with MUST (r = 0.3, p = 0.04), MNA-SF (r = −0.42, p = 0.02), and hospitalization length (r = 0.44, p = 0.001). Delirium, malnutrition, and frailty are correlated in COVID-19 survivors. Screening for these geriatric syndromes should be incorporated in routine clinical practice.
- Subjects
ITALY; DIAGNOSIS of delirium; PNEUMONIA; PATIENT aftercare; LENGTH of stay in hospitals; FRAIL elderly; COVID-19; SYNDROMES; PATIENTS; TERTIARY care; HOSPITAL admission &; discharge; HOSPITAL mortality; RISK assessment; DELIRIUM; MALNUTRITION; DESCRIPTIVE statistics; DISCHARGE planning; DISEASE risk factors
- Publication
Nutrients, 2023, Vol 15, Issue 22, p4727
- ISSN
2072-6643
- Publication type
Article
- DOI
10.3390/nu15224727