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- Title
The Effect of Dietary Advice Aimed at Increasing Protein Intake on Oral Health and Oral Microbiota in Older Adults: A Randomized Controlled Trial.
- Authors
Fluitman, Kristina S.; van den Broek, Tim; Reinders, Ilse; Wijnhoven, Hanneke A. H.; Nieuwdorp, Max; Visser, Marjolein; IJzerman, Richard G.; Keijser, Bart J. F.
- Abstract
Nutrition and oral health are closely related, especially in older adults in whom poor nutrition may lead to oral microbial perturbations, exacerbating poor oral health. In a 6-month randomized controlled trial, we evaluated the effects on oral microbiota and on oral health of dietary advice aimed at increasing protein intake to ≥1.2 g/kg adjusted body weight/day (g/kg aBW/d) in community-dwelling older adults with low habitual protein intake (<1.0 g/kg aBW/d). Food intake was measured via 24 h dietary recalls, oral health was measured via questionnaires, and oral microbial composition was assessed via the 16S rRNA sequencing of tongue swabs. Mean baseline protein intake was 0.8 g/kg aBW/day in both groups. In the high protein group (n = 47), participants increased their protein intake to mean 1.2 g/kg aBW/day at the 6-month follow-up. Protein intake in the control group (n = 43) remained at 0.9 g/kg a BW/day. The intervention did not affect self-reported oral health. While it caused moderate shifts in oral microbiota alpha- and beta-diversity measures, abundances of individual bacterial taxa were not affected. In conclusion, our intervention did not affect self-reported oral health within a period of 6 months, nor did it substantially affect the tongue microbiota composition.
- Subjects
RESEARCH; COMPUTER software; CONFIDENCE intervals; ORAL health; CROSS-sectional method; REGRESSION analysis; MANN Whitney U Test; RISK assessment; T-test (Statistics); MALNUTRITION; HUMAN microbiota; RESEARCH funding; DESCRIPTIVE statistics; CHI-squared test; DENTAL caries; DIETARY proteins; DISEASE risk factors; OLD age
- Publication
Nutrients, 2023, Vol 15, Issue 21, p4567
- ISSN
2072-6643
- Publication type
Article
- DOI
10.3390/nu15214567