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- Title
Two Gold Kiwifruit Daily for Effective Treatment of Constipation in Adults—A Randomized Clinical Trial.
- Authors
Bayer, Simone B.; Heenan, Phoebe; Frampton, Chris; Wall, Catherine L.; Drummond, Lynley N.; Roy, Nicole C.; Gearry, Richard B.
- Abstract
Chronic constipation is highly prevalent worldwide and may be managed with two green or three gold kiwifruit daily. It is unknown whether a smaller standard serve of gold kiwifruit (two daily) is as effective in constipation management. The study aimed to improve chronic constipation with two gold kiwifruit and psyllium in lieu of a placebo daily over four weeks. Adult participants (18–65 years) with functional constipation (FC, n = 11), constipation-predominant irritable bowel syndrome (IBS-C, n = 13), and healthy controls (n = 32) were block-randomized to the treatment order: gold kiwifruit (2/day) or psyllium (fiber-matched, 7.5 g/day) for four weeks, followed by four weeks washout before crossover. Outcomes included alterations of Gastrointestinal Symptom Rating Scale (GSRS) domains and weekly complete spontaneous bowel movements (CSBM) as part of a larger study. Both interventions reduced GSRS constipation domain scores in all subjects compared to baseline values (p = 0.004). All participants reported significantly more weekly CSBM (p = 0.014). Two gold kiwifruit decreased straining (p = 0.021). Two gold kiwifruit daily are as effective as fiber-matched psyllium in treating constipation in adults and should be considered as a treatment option.
- Subjects
INFLAMMATORY bowel diseases; CONSTIPATION; KIWIFRUIT; DEFECATION; TREATMENT effectiveness; RANDOMIZED controlled trials; PSYLLIUM (Plants); DESCRIPTIVE statistics; STATISTICAL sampling
- Publication
Nutrients, 2022, Vol 14, Issue 19, p4146
- ISSN
2072-6643
- Publication type
Article
- DOI
10.3390/nu14194146