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- Title
The Effect of Ziyin Mingmu Pill on the Ultrastructure of Retina in Rats with Light Injury.
- Authors
Xiaoli Zeng; Hongbin Lv; Xuewen Huang
- Abstract
To explore the effect of Ziyin Mingmu pill on the ultrastructure of retina in rats with light injury, and analyze its target and mechanism. 60 rats were randomly divided into two groups, 30 rats in each group. The control group was fed with normal feeding every day, and the observation group was fed with Ziyin Mingmu pill. After 2 weeks, the retina of rats was removed. The pathological changes of retina, the activities of total superoxide dismutase (T-SOD), glutathione peroxidase (GSH PX), catalase (CAT) and the content of malondialdehyde (MDA) were compared between the two groups. Compared with the control group, the pathological morphology of retina in the observation group was significantly reduced, and the difference was statistically significant (P < 0.05). Compared with the control group, the total superoxide dismutase (T-SOD) of the observation group increased significantly, the difference was statistically significant (P < 0.05). Compared with the control group, the glutathione peroxidase (GSH PX) in the observation group increased significantly, the difference was statistically significant (P < 0.05). Compared with the control group, the activity of catalase (CAT) in the observation group increased significantly (P < 0.05). Ziyin Mingmu pill can improve the damage of retina ultrastructure, inhibit the oxidative damage of retina and repair the visual function.
- Subjects
RETINA; CONTROL groups; SUPEROXIDE dismutase; GLUTATHIONE peroxidase; CATALASE
- Publication
Acta Microscopica, 2020, Vol 29, Issue 5, p2667
- ISSN
0798-4545
- Publication type
Article