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- Title
Fecal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-Cov-2) RNA Is Associated With Decreased Coronavirus Disease 2019 (COVID-19) Survival.
- Authors
Adhikari, Upasana Das; Eng, George; Farcasanu, Mara; Avena, Laura E; Choudhary, Manish C; Triant, Virginia A; Flagg, Meaghan; Schiff, Abigail E; Gomez, Isabella; Froehle, Leah M; Diefenbach, Thomas J; Ronsard, Larance; Lingwood, Daniel; Lee, Grace C; Rabi, Seyed Alireza; Erstad, Derek; Velmahos, George; Li, Jonathan Z; Hodin, Richard; Stone, James R
- Abstract
The clinical significance of severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) RNA in stool remains uncertain. We found that extrapulmonary dissemination of infection to the gastrointestinal tract, assessed by the presence of SARS-CoV-2 RNA in stool, is associated with decreased coronavirus disease 2019 (COVID-19) survival. Measurement of SARS-CoV-2 RNA in stool may have utility for clinical risk assessment.
- Subjects
REVERSE transcriptase polymerase chain reaction; COVID-19; SARS-CoV-2; LOG-rank test; MICROSCOPY; RNA; MANN Whitney U Test; FISHER exact test; FECES; COMPARATIVE studies; KAPLAN-Meier estimator; FLUORESCENT antibody technique; DESCRIPTIVE statistics; COVID-19 testing; ODDS ratio; POLYMERASE chain reaction
- Publication
Clinical Infectious Diseases, 2022, Vol 74, Issue 6, p1081
- ISSN
1058-4838
- Publication type
Article
- DOI
10.1093/cid/ciab623