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- Title
SEVERE HYPONATREMIA, HYPERTENSION, ACUTE DETERIORATION OF RENAL FUNCTION IN A YOUNG FEMALE WITH LUPUS NEPHRITIS.
- Authors
Saulescu, Ioana; Daia-Iliescu, Sanziana; Constantinescu, C. L.; Borangiu, Andreea; Buzatu, Casandra; Ionescu, Ruxandra; Opris-Belinski, Daniela
- Abstract
Lupus nephritis is one of the most important organ involvement in patients diagnosed with Systemic Lupus Erythematosus (SLE). It requires aggressive and prolonged immunosuppression in order to induce and maintain remission. There is always a risk of adverse events. It is presented the case of a young woman diagnosed with SLE and active lupus nephritis with acute renal failure, who developed persistent hyponatremia after immunosuppression with Cyclophosphamide was started. The case emphases both the need for synthetic immunosuppression as well as the adverse events that may occur during treatment. Close monitoring of the clinical and biological parameters during immunosuppressive therapy is essential as even one minimally modified parameter may prove important in the evolution of the case. Measures to prevent one side effect do not prevent the developing of other.
- Subjects
LUPUS nephritis; IMMUNOSUPPRESSION; CYCLOPHOSPHAMIDE; ADVERSE health care events; WOMEN patients; DISEASE risk factors
- Publication
Romanian Journal of Rheumatology / Revista Romana de Reumatologie, 2017, Vol 26, Issue 4, p179
- ISSN
1843-0791
- Publication type
Article