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- Title
The second COVID‐19 mRNA vaccine dose enhances the capacity of Spike‐specific memory B cells to bind Omicron BA.2.
- Authors
Hartley, Gemma E.; Edwards, Emily S. J.; Varese, Nirupama; Boo, Irene; Aui, Pei M.; Bornheimer, Scott J.; Hogarth, P. Mark; Drummer, Heidi E.; O'Hehir, Robyn E.; van Zelm, Menno C.
- Abstract
RBD-specific Bmem were detected in all donors after first and second doses, with significantly higher numbers (1.7-fold) post-dose 2 (Figure 1F, Figure S1A-D). The second COVID-19 mRNA vaccine dose enhances the capacity of Spike-specific memory B cells to bind Omicron BA.2 (A) Participants were sampled pre-BNT162b2 vaccination, 3 weeks post-dose 1, and 4 weeks post-dose 2 with a median of 23 days (range: 21-39 days) between doses.
- Subjects
IMMUNOLOGIC memory; SARS-CoV-2 Omicron variant; COVID-19 vaccines; BOOSTER vaccines; SARS-CoV-2
- Publication
Allergy, 2023, Vol 78, Issue 3, p855
- ISSN
0105-4538
- Publication type
Article
- DOI
10.1111/all.15624