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- Title
Magnetic resonance-defined periportal steatosis following intraportal islet transplantation: a functional footprint of islet graft survival?
- Authors
Markmann, James F.; Rosen, Mark; Siegelman, Evan S.; Soulen, Michael C.; Deng, Shaoping; Barker, Clyde F.; Naji, Ali
- Abstract
There is growing interest in more widespread application of isolated islet transplantation for the treatment of type 1 diabetes; however, the sequelae of long-term islet residence within the liver are unknown. We report herein a consequence of intraportal islet transplantation, specifically the development of periportal hepatic steatosis apparently induced by the local secretion of insulin within the liver.
- Subjects
ISLANDS of Langerhans transplantation; TREATMENT of diabetes; FATTY degeneration
- Publication
Diabetes, 2003, Vol 52, Issue 7, p1591
- ISSN
0012-1797
- Publication type
journal article
- DOI
10.2337/diabetes.52.7.1591