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- Title
Induction of Endothelin-1 Expression by Glucose.
- Authors
Park, Joong-Yeol; Takahara, Noriko; Gabriele, Annarita; Chou, Eva; Naruse, Keiko; Suzuma, Kiyoshi; Yamauchi, Teruaki; Ha, Sung-Woo; Meier, Matthias; Rhodes, Christopher J.; King, George L.
- Abstract
Determines the mechanism by which glucose increases endothelin-1 (ET-1) expression and secretion in the bovine retinal cells. Effect of glucose elevation on protein kinase C activities and ET-1 expression; Role of PKC activation in glucose-induced ET-1 expression; Reversibility of PKC activation induced by glucose; Significance of PKC isoforms on ET-1 secretion.
- Subjects
ENDOTHELINS; GENE expression; GLUCOSE; PROTEIN kinase C
- Publication
Diabetes, 2000, Vol 49, Issue 7, p1239
- ISSN
0012-1797
- Publication type
Article
- DOI
10.2337/diabetes.49.7.1239