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- Title
Opening up to cAMP Transport Mechanisms in Airway Smooth Muscle.
- Authors
Huff, Ryan D.; Hirota, Jeremy A.
- Abstract
The authors discuss a study by G. Cao and colleagues which used primary human airway smooth muscle cells from tracheas in observational and mechanistic experimental approaches to characterize the expression and function of ABCC1. Topics include the earliest asthma medications reported, cytoskeleton properties of human airway smooth muscle cells, and a discussion on major translational findings of ABCC1 function as a cAMP exporter in human airway smooth muscle.
- Subjects
SMOOTH muscle; TRACHEA; ASTHMA treatment; MUSCLE cells
- Publication
American Journal of Respiratory Cell & Molecular Biology, 2022, Vol 66, Issue 1, p10
- ISSN
1044-1549
- Publication type
Editorial
- DOI
10.1165/rcmb.2021-0413ED