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- Title
Pharmacognostic, phytochemical, biological and spectroscopic analyses of Capparis decidua (Forsk.) Edgew root and stem bark.
- Authors
Wazir, Muhammad Asif; Azhar, Muhammad Iqbal; Mehmood, Zafar Alam; Qadir, Muhammad Imran; Khan, M. Younis; Siddique, Faheem Ahmad; Shaheer, Talal; Hussain, Waqar; Abbas, Khizar
- Abstract
Purpose: To investigate the pharmacognostic, phytochemical, biological and spectroscopic analyses of Capparis decidua (Forsk.) Edgew root and stem bark. Methods: Plant material (root and stem bark) was collected, authenticated, shade-dried and extracted by maceration using methanol as a solvent separately. Powder microscopy was performed using a binocular microscope. Fluorescence, physico-chemical analysis and phytochemical screening for the presence of secondary metabolites were performed using standard methods. Brine shrimp lethality bioassay was carried out using Artemia salina bioassay, while enzymatic modulatory study was performed by a-amylase inhibition assay. Microscopic analysis was carried out with scanning electron microscopy. Spectroscopic analysis was performed by Fourier transform infrared spectroscopy (FTIR). Results: Powder microscopy showed the presence of different cellular structures. Various colors were observed under ultraviolet (UV) and ordinary light when treated with different reagents. Phytochemical screening revealed the presence of alkaloids, tannins, saponins and flavonoids but phenol and cardiac glycosides were absent from both extracts. The root bark of the plant showed significant brine shrimp lethality activity. Conclusion: Capparis decidua (Forsk.) Edgew root and stem bark contain a variety of bioactive compounds that have medicinal and therapeutic potentials. Therefore, further investigations are required to elucidate their pharmacological properties.
- Subjects
PHYTOCHEMICALS; DECIDUA; FOURIER transform infrared spectroscopy; MICROSCOPY; CARDIAC glycosides; BARK; GAS chromatography/Mass spectrometry (GC-MS)
- Publication
Tropical Journal of Pharmaceutical Research, 2020, Vol 19, Issue 12, p2667
- ISSN
1596-5996
- Publication type
Article
- DOI
10.4314/tjpr.v19i12.27