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- Title
Espectroscopia por ressonância magnética no diagnóstico do câncer de próstata: experiência inicial.
- Authors
de Farias e Melo, Homero José; Szejnfeld, Denis; Paiva, Cristiano Silveira; Abdala, Nitamar; de Arruda, Homero Oliveira; Goldman, Suzan Menasce; Szejnfeld, Jacob
- Abstract
OBJECTIVE: To report an experiment involving the introduction of a protocol utilizing commercially available three-dimensional 1H magnetic resonance spectroscopy imaging (3D 1H MRSI) method in patients diagnosed with prostatic tumors under suspicion of neoplasm. MATERIALS AND METHODS: Forty-one patients in the age range between 51 and 80 years (mean, 67 years) were prospectively evaluated. The patients were divided into two groups: patients with one or more biopsies negative for cancer and high specific-prostatic antigen levels (group A), and patients with cancer confirmed by biopsy (group B). The determination of the targetarea (group A) or the known cancer extent (group B) was based on magnetic resonance imaging and MRSI studies. RESULTS: The specificity of MRSI in the diagnosis of prostate cancer was lower than the specificity reported in the literature (about 47%). On the other hand, for tumor staging, it corresponded to the specificity reported in the literature. CONCLUSION: The introduction and standardization of 3D 1H MRSI has allowed the obtention of a presumable diagnosis of prostate cancer, by a combined analysis of magnetic resonance imaging and metabolic data from 3D 1H MRSI.
- Subjects
MEDICAL research; MEDICAL experimentation on humans; DISEASES in men; PROSTATE tumors; PROSTATE cancer; DIAGNOSIS; MAGNETIC resonance imaging; SPECTRUM analysis; PLASMA spectroscopy; BIOPSY
- Publication
Radiologia Brasileira, 2009, Vol 42, Issue 1, p1
- ISSN
0100-3984
- Publication type
Article
- DOI
10.1590/S0100-39842009000100003