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- Title
Clostridium difficile colitis associated with a 'triple' regimen, containing clarithromycin and metronidazole, to eradicate Helicobacter pylori.
- Authors
Archimandritis; Souyioultzis; Katsorida; Tzivras; Archimandritis, A; Souyioultzis, S; Katsorida, M; Tzivras, M
- Abstract
We describe a 54-year-old man with Helicobacter pylori (+) duodenal ulcer who developed Clostridium difficile associated colitis, 5 days after commencing a 'triple' regimen consisting of omeprazole 20 mg b.d., metronidazole 500 mg b.d. and clarithromycin 500 mg b.d., to eradicate H. pylori. Despite the fact that oral metronidazole did not prevent the disease, the patient did well after treatment with oral metronidazole plus a yeast preparation (Saccharomyces bulardii). No relapse occurred.
- Subjects
DUODENAL ulcers; HELICOBACTER pylori infections; CLOSTRIDIOIDES difficile; COLITIS; SIDE effects of antibiotics; PATIENTS
- Publication
Journal of Internal Medicine, 1998, Vol 243, Issue 3, p251
- ISSN
0954-6820
- Publication type
journal article
- DOI
10.1046/j.1365-2796.1998.00272.x