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- Title
Improved aortic pulse wave velocity assessment from multislice two-directional in-plane velocity-encoded magnetic resonance imaging.
- Authors
Westenberg, Jos J.M.; de Roos, Albert; Grotenhuis, Heynric B.; Steendijk, Paul; Hendriksen, Dennis; van den Boogaard, Pieter J.; van der Geest, Rob J.; Bax, Jeroen J.; Jukema, J. Wouter; Reiber, Johan H.C.
- Abstract
Purpose To evaluate the accuracy and reproducibility of aortic pulse wave velocity (PWV) assessment by in-plane velocity-encoded magnetic resonance imaging (MRI). Materials and Methods In 14 patients selected for cardiac catheterization on suspicion of coronary artery disease and 15 healthy volunteers, PWV was assessed with multislice two-directional in-plane velocity-encoded MRI (PWVi.p.) and compared with conventionally assessed PWV from multisite one-directional through-plane velocity-encoded MRI (PWVt.p.). In patients, PWV was also obtained from intraarterially acquired pressure-time curves (PWVpressure), which is considered the gold standard reference method. In volunteers, PWVi.p. and PWVt.p. were obtained in duplicate in the same examination to test reproducibility. Results In patients, PWVi.p. showed stronger correlation and similar variation with PWVpressure than PWVt.p. (Pearson correlation r = 0.75 vs. r = 0.58, and coefficient of variation [COV] = 10% vs. COV = 12%, respectively). In volunteers, repeated PWVi.p. assessment showed stronger correlation and less variation than repeated PWVt.p. (proximal aorta: r = 0.97 and COV = 10% vs. r = 0.69 and COV = 17%; distal aorta: r = 0.94 and COV = 12% vs. r = 0.90 and COV = 16%; total aorta: r = 0.97 and COV = 7% vs. r = 0.90 and COV = 13%). Conclusion PWVi.p. is an improvement over conventional PWVt.p. by showing higher agreement as compared to the gold standard (PWVpressure) and higher reproducibility for repeated MRI assessment. J. Magn. Reson. Imaging 2010;32:1086-1094. © 2010 Wiley-Liss, Inc.
- Publication
Journal of Magnetic Resonance Imaging, 2010, Vol 32, Issue 5, p1086
- ISSN
1053-1807
- Publication type
Article
- DOI
10.1002/jmri.22359