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Phosphoproteomics revealed cellular signals immediately responding to disruption of cancer amino acid homeostasis induced by inhibition of l-type amino acid transporter 1.
- Published in:
- Cancer & Metabolism, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40170-022-00295-8
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- Publication type:
- Article
L-type amino-acid transporter 1 as a novel biomarker for high-grade malignancy in prostate cancer.
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- Pathology International, 2009, v. 59, n. 1, p. 7, doi. 10.1111/j.1440-1827.2008.02319.x
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- Publication type:
- Article
Expression of L-type amino acid transporter 1 is a poor prognostic factor for Non-Hodgkin's lymphoma.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-00811-8
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- Publication type:
- Article
Human urate transporter 1 (hURAT1) mediates the transport of orotate.
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- Journal of Physiological Sciences, 2011, v. 61, n. 3, p. 253, doi. 10.1007/s12576-011-0136-0
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- Publication type:
- Article
Amino acid transporter LAT1 in tumor-associated vascular endothelium promotes angiogenesis by regulating cell proliferation and VEGF-A-dependent mTORC1 activation.
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- Journal of Experimental & Clinical Cancer Research (17569966), 2020, v. 39, n. 1, p. 1, doi. 10.1186/s13046-020-01762-0
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- Publication type:
- Article
Identification of a Novel Organic Anion Transporter Mediating Carnitine Transport in Mouse Liver and Kidney.
- Published in:
- Cellular Physiology & Biochemistry (Karger AG), 2010, v. 25, n. 4/5, p. 511, doi. 10.1159/000303060
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- Publication type:
- Article
Functional and Immunochemical Characterization of a Novel Organic Anion Transporter Oat8 (Slc22a9) in Rat Renal Collecting Duct.
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- Cellular Physiology & Biochemistry (Karger AG), 2008, v. 21, n. 4, p. 269, doi. 10.1159/000129385
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- Publication type:
- Article
Biomarker Analyses in Patients With Advanced Solid Tumors Treated With the LAT1 Inhibitor JPH203.
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- In Vivo, 2020, v. 34, n. 5, p. 2595, doi. 10.21873/invivo.12077
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- Publication type:
- Article
Mutations in SLC4A4 cause permanent isolated proximal renal tubular acidosis with ocular abnormalities.
- Published in:
- Nature Genetics, 1999, v. 23, n. 3, p. 264, doi. 10.1038/15440
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- Publication type:
- Article
Children’s toxicology from bench to bed - Drug-induced Renal Injury (3): Drug transporters and toxic nephropathy in childhood.
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- Journal of Toxicological Sciences, 2009, v. 34, p. SP259, doi. 10.2131/jts.34.SP259
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- Publication type:
- Article
First-in-human phase I study of JPH203, an L-type amino acid transporter 1 inhibitor, in patients with advanced solid tumors.
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- Investigational New Drugs, 2020, v. 38, n. 5, p. 1495, doi. 10.1007/s10637-020-00924-3
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- Publication type:
- Article
High expression of L-type amino-acid transporter 1 (LAT1) in gastric carcinomas: Comparison with non-cancerous lesions.
- Published in:
- Pathology International, 2011, v. 61, n. 5, p. 281, doi. 10.1111/j.1440-1827.2011.02650.x
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- Publication type:
- Article
EFFECT OF CHRONIC K[sup +] DEFICIENCY ON CONTRACTILE PROPERTIES OF SOLEUS MUSCLE IN RATS: EVIDENCE OF SEX DIFFERENCES.
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- Clinical & Experimental Pharmacology & Physiology, 1999, v. 26, n. 4, p. 323, doi. 10.1046/j.1440-1681.1999.03036.x
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- Publication type:
- Article
Gene expression profiles in t24 human bladder carcinoma cells by inhibiting an l-type amino acid transporter, lat1.
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- Archives of Pharmacal Research, 2007, v. 30, n. 4, p. 444, doi. 10.1007/BF02980218
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- Publication type:
- Article
Reabsorption of neutral amino acids mediated by amino acid transporter LAT2 and TAT1 in the basolateral membrane of proximal tubule.
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- Archives of Pharmacal Research, 2005, v. 28, n. 4, p. 421, doi. 10.1007/BF02977671
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- Publication type:
- Article
Mutations in Human Urate Transporter 1 Gene in Presecretory Reabsorption Defect Type of Familial Renal Hypouricemia.
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- Journal of Clinical Endocrinology & Metabolism, 2005, v. 90, n. 4, p. 2169, doi. 10.1210/jc.2004-1111
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- Publication type:
- Article
Invariant NKT cells metabolically adapt to the acute myeloid leukaemia environment.
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- Cancer Immunology, Immunotherapy, 2023, v. 72, n. 3, p. 543, doi. 10.1007/s00262-022-03268-4
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- Publication type:
- Article
Elimination of Organic Anions in Response to an Early Stage of Renal Ischemia-Reperfusion in the Rat: Role of Basolateral Plasma Membrane Transporters and Cortical Renal Blood Flow.
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- Pharmacology, 2007, v. 81, n. 2, p. 127, doi. 10.1159/000110555
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- Publication type:
- Article
Establishment of a mouse clonal early proximal tubule cell line and outer medullary collecting duct cells expressing P2 purinoceptors.
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- IUBMB Life, 1998, v. 44, n. 4, p. 657, doi. 10.1080/15216549800201702
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- Publication type:
- Article
V1a receptor mRNA expression in mouse early proximal tubule (S1) cell line is regulated by protein kinase A.
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- IUBMB Life, 1998, v. 44, n. 5, p. 961, doi. 10.1080/15216549800202022
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- Publication type:
- Article
Attenuation of renomedullary phospholipase C isozyme, PLC-δ1, in spontaneously hypertensive rats.
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- IUBMB Life, 1997, v. 43, n. 4, p. 741, doi. 10.1080/15216549700204551
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- Publication type:
- Article
Staurosporine-induced apoptosis of immortalized mouse proximal tubule cells is modulated by bcl-2 expression level.
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- IUBMB Life, 1997, v. 42, n. 4, p. 649, doi. 10.1080/15216549700203061
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- Publication type:
- Article
Thromboxane A2 mediates cisplatin-induced apoptosis of renal tubule cells.
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- IUBMB Life, 1997, v. 42, n. 1, p. 113, doi. 10.1080/15216549700202491
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- Publication type:
- Article
ATP-induced calcium mobilization in glomerular mesangial cells is mediated by P2U purinoceptor.
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- IUBMB Life, 1996, v. 39, n. 6, p. 1193, doi. 10.1080/15216549600201382
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- Publication type:
- Article
Isolation by monoclonal antibody of intercalated cells of rabbit kidney.
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- Kidney International, 1988, v. 33, n. 2, p. 543, doi. 10.1038/ki.1988.32
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- Publication type:
- Article
Mutational and functional analysis of SLC4A4 in a patient with proximal renal tubular acidosis.
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- Pflügers Archiv: European Journal of Physiology, 2004, v. 448, n. 4, p. 438, doi. 10.1007/s00424-004-1278-1
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- Publication type:
- Article
The SLC22 drug transporter family.
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- Pflügers Archiv: European Journal of Physiology, 2004, v. 447, n. 5, p. 666, doi. 10.1007/s00424-003-1089-9
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- Publication type:
- Article
CATs and HATs: the SLC7 family of amino acid transporters.
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- Pflügers Archiv: European Journal of Physiology, 2004, v. 447, n. 5, p. 532, doi. 10.1007/s00424-003-1086-z
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- Publication type:
- Article
Intracellular pH regulatory mechanism in a human renal proximal cell line (HKC-8): evidence for Na<sup>+</sup>/H<sup>+</sup> exchanger, Cl<sup>–</sup>/HCO<sub>3</sub><sup>–</sup> exchanger and Na<sup>+</sup>-HCO<sub>3</sub><sup>–</sup> cotransporter
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- Pflügers Archiv: European Journal of Physiology, 2000, v. 440, n. 5, p. 713, doi. 10.1007/s004240000356
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- Publication type:
- Article
The multispecific organic anion transporter (OAT) family.
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- Pflügers Archiv: European Journal of Physiology, 2000, v. 440, n. 3, p. 337, doi. 10.1007/s004240000297
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- Publication type:
- Article
High expression of L-type amino acid transporter 1 as a prognostic marker in bile duct adenocarcinomas.
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- Cancer Medicine, 2014, v. 3, n. 5, p. 1246, doi. 10.1002/cam4.272
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- Publication type:
- Article
Pharmacologic inhibition of LAT1 predominantly suppresses transport of large neutral amino acids and downregulates global translation in cancer cells.
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- Journal of Cellular & Molecular Medicine, 2022, v. 26, n. 20, p. 5246, doi. 10.1111/jcmm.17553
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- Article
Inhibition of the amino‐acid transporter LAT1 demonstrates anti‐neoplastic activity in medulloblastoma.
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- Journal of Cellular & Molecular Medicine, 2019, v. 23, n. 4, p. 2711, doi. 10.1111/jcmm.14176
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- Article
JPH203, a selective L-type amino acid transporter 1 inhibitor, induces mitochondria-dependent apoptosis in Saos2 human osteosarcoma cells.
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- Korean Journal of Physiology & Pharmacology, 2017, v. 21, n. 6, p. 599, doi. 10.4196/kjpp.2017.21.6.599
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- Publication type:
- Article
L-type amino acid transporter 1 expression is a prognostic marker in patients with surgically resected stage I non-small cell lung cancer.
- Published in:
- Histopathology, 2009, v. 54, n. 7, p. 804, doi. 10.1111/j.1365-2559.2009.03300.x
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- Publication type:
- Article
Metabolic Acidosis Alters Expression of Slc22 Transporters in Mouse Kidney.
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- Kidney & Blood Pressure Research, 2020, v. 45, n. 2, p. 263, doi. 10.1159/000506052
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- Article
Evaluation of thoracic tumors with.
- Published in:
- International Journal of Cancer, 2009, v. 124, n. 5, p. 1152, doi. 10.1002/ijc.24034
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- Publication type:
- Article
L-type amino acid transporter 1 as a potential molecular target in human astrocytic tumors.
- Published in:
- International Journal of Cancer, 2006, v. 119, n. 3, p. 484, doi. 10.1002/ijc.21866
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- Publication type:
- Article
Transport of 3-Fluoro-L-α-Methyl-Tyrosine by Tumor-Upregulated L-Type Amino Acid Transporter 1: A Cause of the Tumor Uptake in PET.
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- Journal of Nuclear Medicine, 2012, v. 53, n. 8, p. 1253, doi. 10.2967/jnumed.112.103069
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- Publication type:
- Article
Drug transport studies by human MDR1 in Xenopus laevis oocyte expression system.
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- FASEB Journal, 2008, v. 22, p. 633, doi. 10.1096/fasebj.22.2_supplement.633
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- Publication type:
- Article
Reduced albumin reabsorption in the proximal tubule of early-stage diabetic rats.
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- Histochemistry & Cell Biology, 2001, v. 116, n. 3, p. 269, doi. 10.1007/s004180100317
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- Publication type:
- Article
Molecular identification of a renal urate-anion exchanger that regulates blood urate levels.
- Published in:
- Nature, 2002, v. 417, n. 6887, p. 447, doi. 10.1038/nature742
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- Publication type:
- Article
Roles of Organic Anion Transporters in the Renal Excretion of Perfluorooctanoic Acid.
- Published in:
- Basic & Clinical Pharmacology & Toxicology, 2008, v. 103, n. 1, p. 1, doi. 10.1111/j.1742-7843.2007.00155.x
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- Publication type:
- Article
The W258X mutation in SLC22A12 is the predominant cause of Japanese renal hypouricemia.
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- Pediatric Nephrology, 2004, v. 19, n. 7, p. 728, doi. 10.1007/s00467-004-1424-1
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- Publication type:
- Article
Potent human uric acid transporter 1 inhibitors: in vitro and in vivo metabolism and pharmacokinetic studies.
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- Drug Design, Development & Therapy, 2012, v. 6, p. 323, doi. 10.2147/DDDT.S35805
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- Publication type:
- Article
T-1095, an inhibitor of renal Na+-glucose cotransporters, may provide a novel approach to treating diabetes.
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- 1999
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- Publication type:
- journal article
Roles of organic anion transporters (OATs) and a urate transporter (URAT1) in the pathophysiology of human disease.
- Published in:
- Clinical & Experimental Nephrology, 2005, v. 9, n. 3, p. 195, doi. 10.1007/s10157-005-0368-5
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- Publication type:
- Article
Expression of LAT1 predicts risk of progression of transitional cell carcinoma of the upper urinary tract.
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- Virchows Archiv: European Journal of Pathology, 2007, v. 451, n. 3, p. 681, doi. 10.1007/s00428-007-0457-9
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- Publication type:
- Article
Expression and function of Oat1 and Oat3 in rat kidney exposed to mercuric chloride.
- Published in:
- Archives of Toxicology, 2009, v. 83, n. 10, p. 887, doi. 10.1007/s00204-009-0445-8
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- Publication type:
- Article
Amino acid transporters: molecular structure and physiological roles.
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- Nephrology Dialysis Transplantation, 2000, v. 15, p. 9, doi. 10.1093/ndt/15.suppl_6.9
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- Publication type:
- Article